[HTML][HTML] Recommendations, guidelines, and best practice for the use of human induced pluripotent stem cells for neuropharmacological studies of neuropsychiatric …

LD Polit, I Eidhof, RV McNeill, KM Warre-Cornish… - Neuroscience …, 2023 - Elsevier
The number of individuals suffering from neuropsychiatric disorders (NPDs) has increased
worldwide, with 3 million disability-adjusted life-years calculated in 2019. Though research …

The associations of neutrophil–lymphocyte, platelet–lymphocyte, monocyte–lymphocyte ratios and immune-inflammation index with negative symptoms in patients …

M Šagud, Z Madžarac, G Nedic Erjavec… - Biomolecules, 2023 - mdpi.com
Neutrophil–lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR), monocyte–lymphocyte
ratio (MLR) and systemic immune-inflammation index (SII index) are increasingly used as …

Mechanisms of dopamine oxidation and Parkinson's disease

J Segura-Aguilar, I Paris - Handbook of neurotoxicity, 2022 - Springer
Dopamine's ability to oxidize to aminochrome explains why this molecule may be a
neurotoxic compound that induces toxicity in both cell lines and animal models …

Difference in methylation and expression of brain-derived neurotrophic factor in Alzheimer's disease and mild cognitive impairment

K Kouter, M Nikolac Perkovic, G Nedic Erjavec, T Milos… - Biomedicines, 2023 - mdpi.com
Due to the increasing number of progressive dementias in the population, numerous studies
are being conducted that seek to determine risk factors, biomarkers and pathological …

Maternal gut-microbiota impacts the influence of intrauterine environmental stressors on the modulation of human cognitive development and behavior

OI Olasunkanmi, J Aremu, ML Wong, J Licinio… - Journal of Psychiatric …, 2024 - Elsevier
This review examines the longstanding debate of nature and intrauterine environmental
challenges that shapes human development and behavior, with a special focus on the …

Combinations of genes at the 16p11. 2 and 22q11. 2 CNVs contribute to neurobehavioral traits

M Vysotskiy… - PLoS …, 2023 - journals.plos.org
The 16p11. 2 and 22q11. 2 copy number variants (CNVs) are associated with
neurobehavioral traits including autism spectrum disorder (ASD), schizophrenia, bipolar …

In silico evaluation of the binding mechanism of Rhododendron arboreum bioactives against catechol-o-methyltransferase in Parkinson's disease

D Paul, MR D'Souza - Medicinal Plants-International Journal of …, 2023 - indianjournals.com
Parkinson's disease (PD), the second most prevalent neurodegenerative disease affecting
individuals at 50–60 years of age, still does not have any cure. Even the golden therapy for …

Identification of key genes and signaling pathway in the pathogenesis of Huntington's disease via bioinformatics and next generation sequencing data analysis

BM Vastrad, CM Vastrad - bioRxiv, 2024 - biorxiv.org
Huntington's disease (HD) is the primary cause of progressive motor deficits, psychiatric
symptoms, and cognitive impairment. The exact molecular mechanisms of HD pathogenesis …

Bases neuroquímicas de la transmetilación aberrante de neuroaminas y su relación con el metabolismo de la vitamina B12 y el ácido fólico

AB Pomilio, JO Ciprian Ollivier, AA Vitale… - Acta bioquímica …, 2022 - SciELO Argentina
En este trabajo se analizan las alteraciones que pueden ocurrir en el proceso de metilación
vía los ciclos de metionina y de folato, dando lugar a disfunciones que se manifiestan en …

[PDF][PDF] Neuroscience Applied

AC Vernon, E Grünblatt, DP Srivastava - 2023 - core.ac.uk
The number of individuals suffering from neuropsychiatric disorders (NPDs) has increased
worldwide, with 3 million disability-adjusted life-years calculated in 2019. Though research …