Label-free isolation of exosomes using microfluidic technologies

S Hassanpour Tamrin, A Sanati Nezhad, A Sen - ACS nano, 2021 - ACS Publications
Exosomes are cell-derived structures packaged with lipids, proteins, and nucleic acids. They
exist in diverse bodily fluids and are involved in physiological and pathological processes …

[HTML][HTML] Applications of microfluidics and organ-on-a-chip in cancer research

S Regmi, C Poudel, R Adhikari, KQ Luo - Biosensors, 2022 - mdpi.com
Taking the life of nearly 10 million people annually, cancer has become one of the major
causes of mortality worldwide and a hot topic for researchers to find innovative approaches …

Size-based separation methods of circulating tumor cells

SJ Hao, Y Wan, YQ Xia, X Zou, SY Zheng - Advanced drug delivery reviews, 2018 - Elsevier
Circulating tumor cells (CTCs) originate from the primary tumor mass and enter into the
peripheral bloodstream. Compared to other “liquid biopsy” portfolios such as exosome …

[HTML][HTML] Geometric structure design of passive label-free microfluidic systems for biological micro-object separation

H Tang, J Niu, H Jin, S Lin, D Cui - Microsystems & Nanoengineering, 2022 - nature.com
Passive and label-free microfluidic devices have no complex external accessories or
detection-interfering label particles. These devices are now widely used in medical and …

Microfluidics for label-free sorting of rare circulating tumor cells

S Zhu, F Jiang, Y Han, N Xiang, Z Ni - Analyst, 2020 - pubs.rsc.org
Circulating tumor cells (CTCs) have been widely considered as promising novel biomarkers
for molecular research and clinical diagnosis of cancer. However, the sorting of CTCs is very …

[HTML][HTML] Label-free microfluidic sorting of microparticles

J Zhou, P Mukherjee, H Gao, Q Luan… - APL bioengineering, 2019 - pubs.aip.org
Massive growth of the microfluidics field has triggered numerous advances in focusing,
separating, ordering, concentrating, and mixing of microparticles. Microfluidic systems …

Inertial microfluidics: Recent advances

D Huang, J Man, D Jiang, J Zhao, N Xiang - Electrophoresis, 2020 - Wiley Online Library
Inertial microfluidics has attracted significant attentions in last decade due to its superior
advantages of high throughput, label‐and external field‐free operation, simplicity, and low …

Selective particle and cell capture in a continuous flow using micro-vortex acoustic streaming

DJ Collins, BL Khoo, Z Ma, A Winkler, R Weser… - Lab on a Chip, 2017 - pubs.rsc.org
Acoustic streaming has emerged as a promising technique for refined microscale
manipulation, where strong rotational flow can give rise to particle and cell capture. In …

Tunable velocity-based deterministic lateral displacement for efficient separation of particles in various size ranges

A Kheirkhah Barzoki, R Dezhkam, A Shamloo - Physics of Fluids, 2023 - pubs.aip.org
Deterministic lateral displacement (DLD) is a promising method showing great potential in
achieving high-resolution separation of suspended particles based on their size, through the …

A novel viscoelastic-based ferrofluid for continuous sheathless microfluidic separation of nonmagnetic microparticles

J Zhang, S Yan, D Yuan, Q Zhao, SH Tan, NT Nguyen… - Lab on a Chip, 2016 - pubs.rsc.org
Separation of microparticles has found broad applications in biomedicine, industry and
clinical diagnosis. In a conventional aqueous ferrofluid, separation of microparticles usually …