Tertiary lymphoid structures in cancer: Immune mechanisms and clinical implications
S Wang, H Wang, C Li, B Liu, S He, C Tu - MedComm, 2024 - Wiley Online Library
Cancer is a major cause of death globally, and traditional treatments often have limited
efficacy and adverse effects. Immunotherapy has shown promise in various malignancies …
efficacy and adverse effects. Immunotherapy has shown promise in various malignancies …
Revolutionizing head and neck squamous cell carcinoma treatment with nanomedicine in the era of immunotherapy
HX Li, YW Gong, PJ Yan, Y Xu, G Qin, WP Wen… - Frontiers in …, 2024 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is a prevalent malignant tumor globally.
Despite advancements in treatment methods, the overall survival rate remains low due to …
Despite advancements in treatment methods, the overall survival rate remains low due to …
Spatial multiplexed immunofluorescence analysis reveals coordinated cellular networks associated with overall survival in metastatic osteosarcoma
RA Lacinski, SA Dziadowicz, VK Melemai… - Bone Research, 2024 - nature.com
Patients diagnosed with advanced osteosarcoma, often in the form of lung metastases, have
abysmal five-year overall survival rates. The complexity of the osteosarcoma immune tumor …
abysmal five-year overall survival rates. The complexity of the osteosarcoma immune tumor …
Segmentation aware probabilistic phenotyping of single-cell spatial protein expression data
Y Lee, ELY Chen, DCH Chan, A Dinesh… - Nature …, 2025 - nature.com
Spatial protein expression technologies can map cellular content and organization by
simultaneously quantifying the expression of> 40 proteins at subcellular resolution within …
simultaneously quantifying the expression of> 40 proteins at subcellular resolution within …
Type I conventional dendritic cells and CD8+ T cells predict favorable clinical outcome of head and neck squamous cell carcinoma patients
J Kirchner, I Plesca, R Rothe, A Resag, S Löck… - Frontiers in …, 2024 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is one of the most common tumor
entities worldwide, with human papillomavirus (HPV) infection contributing to cancer …
entities worldwide, with human papillomavirus (HPV) infection contributing to cancer …
[HTML][HTML] B cells and tertiary lymphoid structures in tumors: immunity cycle, clinical impact, and therapeutic applications
X Wu, Q Huang, X Chen, B Zhang, J Liang… - Theranostics, 2025 - pmc.ncbi.nlm.nih.gov
Tumorigenesis involves a multifaceted and heterogeneous interplay characterized by
perturbations in individual immune surveillance. Tumor-infiltrating lymphocytes, as …
perturbations in individual immune surveillance. Tumor-infiltrating lymphocytes, as …
Identifying the Spatial Architecture That Restricts the Proximity of CD8+ T Cells to Tumor Cells in Pancreatic Ductal Adenocarcinoma
Y Xia, J Ma, X Yang, D Liu, Y Zhu, Y Zhao, X Fei, D Xu… - Cancers, 2024 - mdpi.com
Simple Summary The proximity to tumor cells is pivotal to the anti-tumor functions of CD8+ T
cells, but the mechanism underlying the regulation of CD8+ T cell spatial distribution …
cells, but the mechanism underlying the regulation of CD8+ T cell spatial distribution …
[HTML][HTML] Architecture of head and neck squamous cell carcinoma tumor microenvironment revealed: can tertiary lymphoid structures predict post-surgery recurrence?
© Translational Cancer Research. All rights reserved. Transl Cancer Res 2024; 13 (2): 484-
489| https://dx. doi. org/10.21037/tcr-23-2098 were surgically resected from patients with …
489| https://dx. doi. org/10.21037/tcr-23-2098 were surgically resected from patients with …
Harnessing Immune Checkpoint Inhibitors Against Gastric Cancer: Charting the Course to Expanded Therapeutic Benefit
DT Chung, DS Tung, TN Dung - … Research and Therapy, 2024 - bmrat.biomedpress.org
Cancer immunotherapy has become a groundbreaking approach in treatment, with immune
checkpoint inhibitors (ICIs) showing exceptional success in blocking the pathways that …
checkpoint inhibitors (ICIs) showing exceptional success in blocking the pathways that …
[HTML][HTML] CXCL family-related classification predicts prognosis and response to immunotherapy in patients with head and neck squamous cell carcinoma based on …
S Gao, X Tang, C Gao, X Gao, X Guo… - Translational Cancer …, 2024 - ncbi.nlm.nih.gov
Background Head and neck squamous cell carcinoma (HNSCC) is the sixth most prevalent
malignant cancer worldwide. The cysteine X cysteine (CXC) chemokine family contains 17 …
malignant cancer worldwide. The cysteine X cysteine (CXC) chemokine family contains 17 …