Male infertility has affected many families around the world. However, due to the mechanism
underlying male reproductive system dysfunction are not completely elucidated, the use of …

The excessive intake of fructose in the regular human diet could be related to global
increases in metabolic disorders. Sugar-sweetened soft drinks, mostly consumed by …

Background: Immunity is the ultimate barrier between foreign stimuli and a host cell.
Unwanted immune responses can threaten the host cells and may eventually damage a vital …

Scope Luteolin, a natural flavonoid, displays protective activities to testicular tissue.
However, the molecular mechanisms are still unclear. In this study, the aim is to identify the …

Abstract Ethnopharmacological relevance Wuzi-Yanzong-Wan (WZYZW) is a classic
Chinese herbal preparation, which has a significant clinical efficacy in tonifying the kidney …

The increased consumption of high-fructose in diet may contribute to high prevalence of
metabolic syndrome in the world. The influence of high-fructose diet on male reproductive …

The consumption of fructose has increased in children and adolescents and is partially
responsible for the high incidence of metabolic diseases. The lifestyle during postnatal …

Background Exposure to ionizing radiation (IR) induces severe damage in multiple human
tissues. The testes are extremely sensitive to IR, and testes irradiation can result in infertility …

Objectives Curcumin is a promising nutraceutical with reported diverse therapeutic
properties, but of limited oral bioavailability. The current manuscript investigates the role of …

Background: This work was designed to clarify, for the first time up to our knowledge, the
effects of high-fructose diet (HFrD)-induced metabolic syndrome (MetS) on the pituitary …