Stimuli-responsive polymers can respond to internal stimuli, such as reactive oxygen
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …

This paper provides a review of the literature on the use of Pluronic® triblock copolymers for
drug encapsulation over the last 10 years. A special focus is given to the progress of drug …

Various formulations of polymeric micelles, tiny spherical structures made of polymeric
materials, are currently being investigated in preclinical and clinical settings for their …

Manipulating intracellular biological processes and organelles has emerged as a pivotal
strategy to influence cellular physiological functions. Mitochondria, recognized as the …

The alarming increase in the number of breast cancer patients worldwide and the increasing
death rate indicate that the traditional and current medicines are insufficient to fight against …

In the modern era, nanomedicine has developed novel drug-delivery strategies to improve
chemotherapy. Nanotechnological-based treatment approaches for cancer through targeted …

Hypoxia is a common feature of most solid tumors, which promotes the proliferation,
invasion, metastasis, and therapeutic resistance of tumors. Researchers have been …

Targeted cancer therapy (TCT) is gaining increased interest because it reduces the risks of
adverse side effects by specifically treating tumor cells. TCT testing has traditionally been …

Glucose-6-phosphate dehydrogenase (G6PD) is a promising target in cancer therapy.
However, poor cellular uptake and off-target toxicity have impeded the clinical translation of …

Despite noteworthy technological progress and promising preclinical trials, brain disorders
are still the leading causes of death globally. Extracellular vesicles (EVs), nano-/micro-sized …