Outliers are also referred to as abnormalities, discordants, deviants, or anomalies in the data mining and statistics literature. In most applications, the data is created by one or more …
Kidney stone disease causes significant morbidity and increases health care utilization. In this work, we decipher the cellular and molecular niche of the human renal papilla in …
FL Coe, EM Worcester, AP Evan - Nature Reviews Nephrology, 2016 - nature.com
The most common presentation of nephrolithiasis is idiopathic calcium stones in patients without systemic disease. Most stones are primarily composed of calcium oxalate and form …
B Hoppe - Nature Reviews Nephrology, 2012 - nature.com
The autosomal recessive inherited primary hyperoxalurias types I, II and III are caused by defects in glyoxylate metabolism that lead to the endogenous overproduction of oxalate …
EJ Espinosa-Ortiz, BH Eisner, D Lange… - Nature Reviews …, 2019 - nature.com
Infection stones are complex aggregates of crystals amalgamated in an organic matrix that are strictly associated with urinary tract infections. The management of patients who form …
Background The role of calcium oxalate crystals and deposits in UTI pathogenesis has not been established. The objectives of this study were to identify bacteria present in pediatric …
S Chaiyarit, V Thongboonkerd - Frontiers in physiology, 2020 - frontiersin.org
Mitochondrion is a pivotal intracellular organelle that plays crucial roles in regulation of energy production, oxidative stress, calcium homeostasis, and apoptosis. Kidney stone …
EAH Allam - African Journal of Urology, 2024 - Springer
Urolithiasis is a multifaceted and common urological disorder characterized by the development of renal calculi. Calcium oxalate stones are the most prevalent type of calculi …
JD Rimer, AM Kolbach-Mandel, MD Ward, JA Wesson - Urolithiasis, 2017 - Springer
The formation of crystal aggregates, one of the critical processes in kidney stone pathogenesis, involves interactions between crystals (predominantly calcium oxalate …