Dietary fibre in gastrointestinal health and disease

SK Gill, M Rossi, B Bajka, K Whelan - Nature Reviews Gastroenterology …, 2021 - nature.com
Epidemiological studies have consistently demonstrated the benefits of dietary fibre on
gastrointestinal health through consumption of unrefined whole foods, such as wholegrains …

[HTML][HTML] The effect of fiber supplementation on chronic constipation in adults: an updated systematic review and meta-analysis of randomized controlled trials

A Van Der Schoot, C Drysdale, K Whelan… - The American journal of …, 2022 - Elsevier
Background Chronic constipation is a prevalent disorder that remains challenging to treat.
Studies suggest increasing fiber intake may improve symptoms, although recommendations …

Design and reporting of prebiotic and probiotic clinical trials in the context of diet and the gut microbiome

K Whelan, M Alexander, C Gaiani, G Lunken… - Nature …, 2024 - nature.com
Diet is a major determinant of the gastrointestinal microbiome composition and function, yet
our understanding of how it impacts the efficacy of prebiotics and probiotics is limited. Here …

Dietary fibres and IBS: translating functional characteristics to clinical value in the era of personalised medicine

D So, PR Gibson, JG Muir, CK Yao - Gut, 2021 - gut.bmj.com
Clinical guidelines in the use of fibre supplementation for patients with IBS provide one-size-
fits-all advice, which has limited value. This narrative review addresses data and concepts …

Psyllium reduces inulin-induced colonic gas production in IBS: MRI and in vitro fermentation studies

D Gunn, Z Abbas, HC Harris, G Major, C Hoad… - Gut, 2022 - gut.bmj.com
Objective Health-promoting dietary fibre including inulin often triggers gastrointestinal
symptoms in patients with IBS, limiting their intake. Our aim was to test if coadministering …

[HTML][HTML] Review of structure and bioactivity of the Plantago (Plantaginaceae) polysaccharides

S Zhang, J Hu, Y Sun, H Tan, J Yin, F Geng, S Nie - Food Chemistry: X, 2021 - Elsevier
Plantago (Plantaginaceae) is an herbal plant, which is used in folk medicine, functional food,
and dietary supplement products. Recent pharmacological and phytochemical studies have …

Associations of fecal short chain fatty acids with colonic transit, fecal bile acid, and food intake in irritable bowel syndrome

MR Waseem, A Shin, R Siwiec… - Clinical and …, 2023 - journals.lww.com
METHODS: We conducted a prospective observational study of fecal SCFA, BAs, and CTT in
healthy controls (HCs) and participants with IBS. We compared study end points across …

Food biopolymer behaviors in the digestive tract: Implications for nutrient delivery

M Zhang, Z Zuo, X Zhang, L Wang - Critical Reviews in Food …, 2024 - Taylor & Francis
Biopolymers are prevalent in both natural and processed foods, serving as thickeners,
emulsifiers, and stabilizers. Although specific biopolymers are known to affect digestion, the …

Small bowel water content assessed by MRI in health and disease: a collation of single‐centre studies

N Dellschaft, C Hoad, L Marciani… - Alimentary …, 2022 - Wiley Online Library
Background New developments in MRI have allowed the non‐invasive, accurate
measurement of the small bowel water content (SBWC). Aims To collate studies measuring …

[HTML][HTML] The impact of psyllium gelation behaviour on in vitro colonic fermentation properties

HC Harris, N Pereira, T Koev, YZ Khimyak… - Food …, 2023 - Elsevier
Psyllium is a viscous, gel forming fibre with properties that have led it to be used for
alleviating gastrointestinal discomfort. We have used previously identified fractions of …