Chemical reactivity from an activation strain perspective

P Vermeeren, TA Hamlin, FM Bickelhaupt - Chemical Communications, 2021 - pubs.rsc.org
Chemical reactions are ubiquitous in the universe, they are at the core of life, and they are
essential for industrial processes. The drive for a deep understanding of how something …

An overview of NRF2-activating compounds bearing α, β-unsaturated moiety and their antioxidant effects

MC Egbujor, B Buttari, E Profumo… - International Journal of …, 2022 - mdpi.com
The surge of scientific interest in the discovery of Nuclear Factor Erythroid 2 (NFE2)-Related
Factor 2 (NRF2)-activating molecules underscores the importance of NRF2 as a therapeutic …

Selective Electrosynthetic hydrocarboxylation of α, β‐unsaturated Esters with Carbon Dioxide

AM Sheta, A Alkayal, MA Mashaly, SB Said… - Angewandte …, 2021 - Wiley Online Library
The carboxylation of low‐value commodity chemicals to provide higher‐value carboxylic
acids is of significant interest. Recently alternative routes to the traditional hydroformylation …

Asymmetric Synthesis of α‐Methylene‐γ‐Butyrolactones via Tandem Allylboration/Lactonization: a Kinetic Resolution Process

Z Tan, L Chen, L Li, Y Li, Y Luo, F Wang… - Angewandte …, 2023 - Wiley Online Library
The α‐methylene‐γ‐butyrolactone motif is a widely encountered unit in many natural
products and pharmaceutical compounds. Herein, a practical and efficient synthesis of α …

Pyridinium‐Derived Mesoionic N‐Heterocyclic Olefins (py‐mNHOs)

Q Sun, A Eitzinger, R Esken, PW Antoni… - Angewandte Chemie …, 2024 - Wiley Online Library
Mesoionic polarization allows access to electron‐rich olefins that have found application as
organocatalysts, ligands, or nucleophiles. Herein, we report the synthesis and …

Regio-and stereoselective divergent cross-coupling of alkynes and disubstituted alkenes via photoredox cobalt dual catalysis

SQ Zhang, YL Li, K Cui, C Chen, ZY Gu… - Organic Chemistry …, 2023 - pubs.rsc.org
Achieving divergent synthesis from the same substrates quickly to generate different
products remains an attractive objective in synthetic chemistry and the medicinal industry …

[HTML][HTML] Enzymatic synthesis of biobased aliphatic-hetero-aromatic furanic copolyesters: Influence of furan dimethyl ester isomerism

F Silvianti, D Maniar, B Agostinho, TC de Leeuw, X Lan… - Polymer, 2024 - Elsevier
Due to environmental concerns, there is a growing demand for more sustainable materials.
As a result, the renewability of the raw materials and catalysts involved in production is …

Direct synthesis of alkylated 4-hydroxycoumarin derivatives via a cascade Cu-catalyzed dehydrogenation/conjugate addition sequence

Z Chen, H Li, Y Liao, M Wang, W Su - Chemical Communications, 2023 - pubs.rsc.org
An efficient approach for the direct synthesis of alkylated 4-hydroxycoumarin derivatives via
a Cu-catalyzed cascade dehydrogenation/conjugate addition sequence starting from simple …

Defining the Synthetic Scope of ortho‐Quinone Methides by Quantifying their Electrophilicity

C Gross, A Eitzinger, N Hampel… - … –A European Journal, 2024 - Wiley Online Library
A series of aryl‐substituted ortho‐quinone methides (oQMs) was synthesised and
structurally characterised. Kinetic studies of the nucleophilic additions of carbanions …

Stereoelectronic Effect in the Reaction of α-Methylene Lactones with Tertiary Phosphines and Its Application in Organocatalysis

AV Salin, AA Shabanov, KR Khayarov… - The Journal of …, 2023 - ACS Publications
The kinetic data indicate that the addition of tertiary phosphines to α-methylene lactones in
acetic acid is strongly accelerated in comparison to the reactions of related open-chain …