Sand flies: Basic information on the vectors of leishmaniasis and their interactions with Leishmania parasites

P Cecílio, A Cordeiro-da-Silva, F Oliveira - Communications biology, 2022 - nature.com
Blood-sucking arthropods transmit a variety of human pathogens acting as disseminators of
the so-called vector-borne diseases. Leishmaniasis is a spectrum of diseases caused by …

Recent updates and perspectives on leishmaniasis

D Savoia - The Journal of Infection in Developing Countries, 2015 - jidc.org
Leishmaniasis is a neglected vector-borne tropical infection considered to be a disease of
the poor. Concentrated in poverty-stricken countries within Southeast Asia, East Africa, and …

Role of cytokines in experimental and human visceral leishmaniasis

M Samant, U Sahu, SC Pandey… - Frontiers in cellular and …, 2021 - frontiersin.org
Visceral Leishmaniasis (VL) is the most fatal form of disease leishmaniasis. To date, there
are no effective prophylactic measures and therapeutics available against VL. Recently, new …

The equivocal role of Th17 cells and neutrophils on immunopathogenesis of leishmaniasis

SC Gonçalves-de-Albuquerque… - Frontiers in …, 2017 - frontiersin.org
Advances in the understanding of leishmaniasis progression indicate that cellular
interactions more complex than the Th1/Th2 paradigm define the course of infection. Th17 …

Salmonella persist in activated macrophages in T cell-sparse granulomas but are contained by surrounding CXCR3 ligand-positioned Th1 cells

MF Goldberg, EK Roeske, LN Ward, T Pengo… - Immunity, 2018 - cell.com
Salmonella enterica (Se) bacteria cause persistent intracellular infections while stimulating a
robust interferon-γ-producing CD4+ T (Th1) cell response. We addressed this paradox of …

[HTML][HTML] Endogenous enzymatic antioxidant defense and pathologies

A Eddaikra, N Eddaikra - Antioxidants-benefits, sources …, 2021 - intechopen.com
Oxidative stress is an important component of various diseases. It manifests as an
imbalance caused by an excessive production of reactive oxygen species (ROS) which are …

[HTML][HTML] Caryocar coriaceum extracts exert leishmanicidal effect acting in promastigote forms by apoptosis-like mechanism and intracellular amastigotes by Nrf2/HO-1 …

F Tomiotto-Pellissier, DR Alves… - Biomedicine & …, 2018 - Elsevier
Leishmania (L.) amazonensis is the American Cutaneous Leishmaniasis-causing agents,
and the available drugs for this disease present toxicity, low efficiency and difficulty of …

Function of macrophage and parasite phosphatases in leishmaniasis

D Soulat, C Bogdan - Frontiers in immunology, 2017 - frontiersin.org
The kinetoplastid protozoan parasites belonging to the genus Leishmania are the causative
agents of different clinical forms of leishmaniasis, a vector-borne infectious disease with …

Escaping deleterious immune response in their hosts: lessons from trypanosomatids

A Geiger, G Bossard, D Sereno, J Pissarra… - Frontiers in …, 2016 - frontiersin.org
The Trypanosomatidae family includes the genera Trypanosoma and Leishmania,
protozoan parasites displaying complex digenetic life cycles requiring a vertebrate host and …

trans-Chalcone modulates Leishmania amazonensis infection in vitro by Nrf2 overexpression affecting iron availability

MM Miranda-Sapla, F Tomiotto-Pellissier… - European Journal of …, 2019 - Elsevier
Leishmania parasites infect macrophages causing a wide spectrum of human diseases
encompassing from cutaneous to visceral forms. The drugs currently used in leishmaniasis …