Disuse osteoporosis describes a state of bone loss due to local skeletal unloading or
systemic immobilization. This review will discuss advances in the field that have shed light …

Bariatric surgery results in long term weight loss and improvement or resolution in obesity
related comorbidities. However, mounting evidence indicates that it adversely affects bone …

Introduction The application of high-resolution peripheral quantitative computed tomography
(HR-pQCT) to assess bone microarchitecture has grown rapidly since its introduction in …

The Bioarchaeology of Metabolic Bone Disease, Second Edition is a comprehensive source
dedicated to better understanding this group of conditions that have significant …

The vast osteocytic network is believed to orchestrate bone metabolic activity in response to
mechanical stimuli through production of sclerostin, RANKL, and osteoprotegerin (OPG) …

Determining the extent of bone recovery after prolonged spaceflight is important for
understanding risks to astronaut long-term skeletal health. We examined bone strength …

Macrophages are multifunctional immune system cells that are essential for the mechanical
stimulation‐induced control of metabolism. Piezo1 is a non‐selective calcium channel …

Mechanical force regulates bone density, modeling, and homeostasis. Substantial periosteal
bone formation is generated by external mechanical stimuli, yet its mechanism is poorly …

Abstract Purpose of Review Patients with inflammatory arthropathies have a high rate of
fragility fractures. Diagnostic assessment and monitoring of bone density and quality are …

Roux‐en‐Y gastric bypass (RYGB) surgery is a highly effective treatment for obesity but
negatively affects the skeleton. Studies of skeletal effects have generally examined areal …