Pseudoenzymes are present within many, but not all, known enzyme families and lack one
or more conserved canonical amino acids that help define their catalytically active …

Plasticity enhances species fitness and survival under climate change. Ocean acidification
poses a potential threat to copepods, a major zooplankton group that serves as a key link …

Inappropriate CD4+ T helper (TH) cell differentiation leads to progression of inflammatory
and autoimmune diseases, yet the regulatory mechanisms governing stability and activity of …

The outbreak of Coronavirus disease 2019 (COVID-19) throughout the world has caused
millions of death, while the dynamics of host responses and the underlying regulation …

Integrating signals is essential for cell survival, leading to the concept of synthetic lethality.
However, how signaling is integrated to control cell migration remains unclear. By …

Background The syncytiotrophoblast (SCT) layer in the placenta serves as a crucial physical
barrier separating maternal-fetal circulation, facilitating essential signal and substance …

Functional Analysis of Estrogen Receptor 1 in Diabetic Wound Healing: A Knockdown Cell-Based
and Bioinformatic Study - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Abstract Tribbles Homolog 1 (TRIB1) is a pseudokinase with a well characterised oncogenic
capacity in acute myeloid leukaemia (AML). Although several transcriptomic studies have …