Advanced fluorescence imaging technology in the near-infrared-II window for biomedical applications

C Li, G Chen, Y Zhang, F Wu… - Journal of the American …, 2020 - ACS Publications
Fluorescence imaging has become a fundamental tool for biomedical applications;
nevertheless, its intravital imaging capacity in the conventional wavelength range (400–950 …

Design of superior phototheranostic agents guided by Jablonski diagrams

G Feng, GQ Zhang, D Ding - Chemical Society Reviews, 2020 - pubs.rsc.org
Phototheranostics represents a promising direction for modern precision medicine, which
has recently attracted great research interest from multidisciplinary research areas. Organic …

Molecular engineering of NIR‐II fluorophores for improved biomedical detection

Z Lei, F Zhang - Angewandte Chemie International Edition, 2021 - Wiley Online Library
The development of fluorophores for the second near‐infrared window (NIR‐II, 1000–1700
nm) represents an emerging, significant, and vibrant field in analytic chemistry, chemical …

Stable, bright, and long-fluorescence-lifetime dyes for deep-near-infrared bioimaging

J Li, Y Dong, R Wei, G Jiang, C Yao, M Lv… - Journal of the …, 2022 - ACS Publications
Near-infrared (NIR) fluorophores absorbing maximally in the region beyond 800 nm, ie,
deep-NIR spectral region, are actively sought for biomedical applications. Ideal dyes are …

Activatable molecular probes for second near‐infrared fluorescence, chemiluminescence, and photoacoustic imaging

J Huang, K Pu - Angewandte Chemie International Edition, 2020 - Wiley Online Library
Optical imaging plays a crucial role in biomedicine. However, due to strong light scattering
and autofluorescence in biological tissue between 650–900 nm, conventional optical …

Engineering of reversible NIR‐II redox‐responsive fluorescent probes for imaging of inflammation in vivo

L He, LH He, S Xu, TB Ren, XX Zhang… - Angewandte …, 2022 - Wiley Online Library
The second near‐infrared (NIR‐II) fluorescent imaging shows great potential for deep tissue
analysis at high resolution in living body owing to low background autofluorescence and …

An Activatable NIR‐II Fluorescent Reporter for In Vivo Imaging of Amyloid‐β Plaques

J Miao, M Miao, Y Jiang, M Zhao, Q Li… - Angewandte Chemie …, 2023 - Wiley Online Library
Fluorescence imaging in the second near‐infrared (NIR‐II) window holds great promise for
in vivo visualization of amyloid‐β (Aβ) pathology, which can facilitate characterization and …

A general strategy for development of activatable NIR‐II fluorescent probes for in vivo high‐contrast bioimaging

TB Ren, ZY Wang, Z Xiang, P Lu, HH Lai… - Angewandte …, 2021 - Wiley Online Library
Organic dye based NIR‐II fluorescent probes, owing to their high signal‐to‐background ratio
and deeper penetration, are highly useful for deep‐tissue high‐contrast imaging in vivo …

Molecular fluorophores for deep-tissue bioimaging

S Wang, B Li, F Zhang - ACS central science, 2020 - ACS Publications
Fluorescence imaging has made tremendous inroads toward understanding the complexity
of biological systems, but in vivo deep-tissue imaging remains a great challenge due to the …

Activity-based fluorescence probes for pathophysiological peroxynitrite fluxes

Z Mao, J Xiong, P Wang, J An, F Zhang, Z Liu… - Coordination Chemistry …, 2022 - Elsevier
Abstract Peroxynitrite (ONOO−), one of the reactive oxygen and nitrogen species (RONS), is
famous for its potent oxidation and nitration capabilities and plays crucial roles in various …