Caffeic acid (CA) and its phenethyl ester (CAPE) are naturally occurring hydroxycinnamic
acids with an interesting array of biological activities; eg, antioxidant, anti-inflammatory …

Sphingomyelinases (SMases) hydrolyse sphingomyelin, releasing ceramide and creating a
cascade of bioactive lipids. These lipids include sphingosine and sphingosine-1-phosphate …

BACKGROUND: The membrane components of cardiomyocytes are rich in polyunsaturated
fatty acids, which are easily oxidized. Thus, an efficient glutathione-based lipid redox system …

Caffeic acid phenethyl ester (CAPE) is an active component of honeybee propolis extracts.
Carbonic anhydrases (CAs, EC 4.2. 1.1) are widespread and intensively studied …

Oxidized cytochrome c is a powerful superoxide scavenger within the mitochondrial IMS
(intermembrane space), but the importance of this role in situ has not been well explored. In …

The toxicity of aminoglycosides including gentamicin (GEN), the most widely used drug in
this category, is believed to be related to the generation of reactive oxygen species (ROS) in …

Angelica sinensis polysaccharides were analyzed using high performance liquid
chromatography (HPLC) and Fourier Transform Infrared (FT-IR). The major sugar of the …

Cardiovascular diseases (CVDs) contribute to major public health issues. Some studies
have found that caffeic acid (CA) and caffeic acid phenethyl ester (CAPE) may effectively …

Ceramide is a sphingolipid that serves as an important second messenger in an increasing
number of stress-induced pathways. Ceramide has long been known to affect the …

The aim of the present study was to evaluate the protective effect of palmatine, one of active
ingredients of Coptidis rhizoma, against myocardial ischemia–reperfusion (I/R) injury is due …