The prefrontal cortex, pathological anxiety, and anxiety disorders

MM Kenwood, NH Kalin, H Barbas - Neuropsychopharmacology, 2022 - nature.com
Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …

Epilepsy and brain network hubs

J Royer, BC Bernhardt, S Larivière, E Gleichgerrcht… - …, 2022 - Wiley Online Library
Epilepsy is a disorder of brain networks. A better understanding of structural and dynamic
network properties may improve epilepsy diagnosis, treatment, and prognostics. Hubs are …

Microstructural and functional gradients are increasingly dissociated in transmodal cortices

C Paquola, R Vos De Wael, K Wagstyl… - PLoS …, 2019 - journals.plos.org
While the role of cortical microstructure in organising neural function is well established, it
remains unclear how structural constraints can give rise to more flexible elements of …

The Structural Model: a theory linking connections, plasticity, pathology, development and evolution of the cerebral cortex

MÁ García-Cabezas, B Zikopoulos… - Brain Structure and …, 2019 - Springer
The classical theory of cortical systematic variation has been independently described in
reptiles, monotremes, marsupials and placental mammals, including primates, suggesting a …

Integrating multimodal and multiscale connectivity blueprints of the human cerebral cortex in health and disease

JY Hansen, G Shafiei, K Voigt, EX Liang, SML Cox… - PLoS …, 2023 - journals.plos.org
The brain is composed of disparate neural populations that communicate and interact with
one another. Although fiber bundles, similarities in molecular architecture, and synchronized …

Multimodal gradients across mouse cortex

BD Fulcher, JD Murray, V Zerbi… - Proceedings of the …, 2019 - National Acad Sciences
The primate cerebral cortex displays a hierarchy that extends from primary sensorimotor to
association areas, supporting increasingly integrated function underpinned by a gradient of …

Intrinsic network architecture predicts the effects elicited by intracranial electrical stimulation of the human brain

KCR Fox, L Shi, S Baek, O Raccah, BL Foster… - Nature human …, 2020 - nature.com
Intracranial electrical stimulation (iES) of the human brain has long been known to elicit a
remarkable variety of perceptual, motor and cognitive effects, but the functional–anatomical …

The natural axis of transmitter receptor distribution in the human cerebral cortex

A Goulas, JP Changeux, K Wagstyl… - Proceedings of the …, 2021 - National Acad Sciences
Transmitter receptors constitute a key component of the molecular machinery for intercellular
communication in the brain. Recent efforts have mapped the density of diverse transmitter …

Heritability and cross-species comparisons of human cortical functional organization asymmetry

B Wan, Ş Bayrak, T Xu, HL Schaare, RAI Bethlehem… - Elife, 2022 - elifesciences.org
The human cerebral cortex is symmetrically organized along large-scale axes but also
presents inter-hemispheric differences in structure and function. The quantified contralateral …

Shifts in myeloarchitecture characterise adolescent development of cortical gradients

C Paquola, RAI Bethlehem, J Seidlitz, K Wagstyl… - elife, 2019 - elifesciences.org
We studied an accelerated longitudinal cohort of adolescents and young adults (n= 234, two
time points) to investigate dynamic reconfigurations in myeloarchitecture. Intracortical …