We have reviewed the literature and have identified more than 100 diseases or conditions
that are associated with raised concentrations of plasma total homocysteine. The …

Homocysteine (Hct) is a substance produced in the metabolism of methionine. It is an
essential type of amino acid gained from the daily diet. Methylenetetrahydrofolate reductase …

Purpose Today's diet consists of a substantial proportion of ultra-processed foods (UPF),
especially in women with overweight and obesity in the reproductive period. High UPF …

One-carbon metabolism is crucial for the maintenance of healthy pregnancy and alterations
in this pathway have been associated with various pregnancy-related complications …

Background Maternal exposure to fine particulate matter (PM2. 5) was associated with
pregnancy complications. However, we still lack comprehensive evidence regarding which …

Due to the spread of the western style diet, which is characterized by high intake of
processed food, micronutrients (vitamins and minerals) deficiency is increasing in the …

Abstract Background/Objectives Observational studies link elevated homocysteine
concentrations (Hcy) with female fertility, pregnancy loss, and low offspring birthweight …

Homocysteine is a marker for derangements in one-carbon metabolism. Elevated
homocysteine may represent a causal link between poor maternal nutrition and impaired …

Hyperhomocysteinemia may arise from folate/vitamin B12 deficiency, genetic
polymorphisms, kidney disease, or hypothyroidism. It is associated with an increased risk of …

The adverse pregnancy outcomes, including recurrent spontaneous abortion (RSA), are
strongly correlated with water-soluble vitamins, but how to predict RSA occurrence using …