This tutorial review presents descriptions of two amyloidogenic proteins, amyloid-β (Aβ)
peptides and islet amyloid polypeptide (IAPP), whose misfolding propensities are implicated …

Alzheimer's disease (AD) is the most common neurodegenerative disease affecting more
than 50 million people worldwide. The pathology of this multifactorial disease is primarily …

Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …

Recent times have witnessed an upsurge in the incidence of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Prion disease, and …

The incidence of neurological diseases, such as Parkinson's disease, Alzheimer's disease
and stroke, is increasing. An increasing number of studies have correlated these diseases …

Brain iron accumulation has been implicated in a host of chronic neurological diseases,
including Parkinson's disease (PD). The elevated iron levels observed in the substantia …

Curcumin, a well-documented phytochemical compound used to treat various diseases
because of its more tolerability in the human body and has no side effects. The present study …

The concept of chelation therapy as a valuable therapeutic approach in neurological
disorders led us to develop multi-target, non-toxic, lipophilic, brain-permeable compounds …

Inflammatory responses involving microglia and astrocytes contribute to the pathogenesis of
neurodegenerative diseases (NDs). In addition, inflammation is tightly linked to iron …

Dysregulation of iron metabolism has been observed in patients with neurodegenerative
diseases (NDs). Utilization of several importers and exporters for iron transport in brain cells …