[HTML][HTML] Magnesium-based biomaterials as emerging agents for bone repair and regeneration: From mechanism to application

H Zhou, B Liang, H Jiang, Z Deng, K Yu - Journal of Magnesium and Alloys, 2021 - Elsevier
Magnesium (Mg) is the fourth most abundant element in the human body and is important in
terms of specific osteogenesis functions. Here, we provide a comprehensive review of the …

Magnesium-based bioceramics in orthopedic applications

M Nabiyouni, T Brückner, H Zhou, U Gbureck… - Acta biomaterialia, 2018 - Elsevier
Magnesium ions are directly involved in numerous biological mechanisms; for example, they
play an important part in the regulation of ion channels, DNA stabilization, enzyme activation …

[HTML][HTML] Magnesium alloys for orthopedic applications: A review on the mechanisms driving bone healing

N Wang, S Yang, H Shi, Y Song, H Sun, Q Wang… - Journal of Magnesium …, 2022 - Elsevier
Magnesium (Mg) alloys have attracted a wealth of attention in orthopedic fields for their
superior mechanical properties, degradability, and excellent biocompatibility. Consistently …

Controlled magnesium ion delivery system for in situ bone tissue engineering

Z Yuan, Z Wan, C Gao, Y Wang, J Huang… - Journal of Controlled …, 2022 - Elsevier
Abstract Magnesium cation (Mg 2+) has been an emerging therapeutic agent for inducing
vascularized bone regeneration. However, the therapeutic effects of current magnesium …

Regulation of immune response by bioactive ions released from silicate bioceramics for bone regeneration

Y Huang, C Wu, X Zhang, J Chang, K Dai - Acta biomaterialia, 2018 - Elsevier
Silicate bioceramics have been considered to possess a wide prospect of clinical
application for orthopedic tissue regeneration due to their excellent osteogenesis and …

Effects of magnesium alloy corrosion on biological response–Perspectives of metal-cell interaction

J Kim, H Pan - Progress in Materials Science, 2023 - Elsevier
Mg alloys are biodegradable metals widely used in orthopedic and cardiovascular
applications because Mg ions are essential trace elements known to induce angiogenesis …

Effects of extracellular magnesium extract on the proliferation and differentiation of human osteoblasts and osteoclasts in coculture

L Wu, F Feyerabend, AF Schilling, R Willumeit-Römer… - Acta biomaterialia, 2015 - Elsevier
Coculture of osteoblasts and osteoclasts is a subject of interest in the understanding of how
magnesium (Mg)-based implants influence the bone metabolism and remodeling upon …

Metal ions: The unfading stars of bone regeneration—From bone metabolism regulation to biomaterial applications

Y Luo, H Liu, Y Zhang, Y Liu, S Liu, X Liu… - Biomaterials Science, 2023 - pubs.rsc.org
In recent years, bone regeneration has emerged as a remarkable field that offers promising
guidance for treating bone-related diseases, such as bone defects, bone infections, and …

Evaluation of the immunomodulatory effects of cobalt, copper and magnesium ions in a pro inflammatory environment

L Díez-Tercero, LM Delgado, E Bosch-Rué… - Scientific reports, 2021 - nature.com
Biomaterials and scaffolds for Tissue Engineering are widely used for an effective healing
and regeneration. However, the implantation of these scaffolds causes an innate immune …

The role of trace elements and minerals in osteoporosis: a review of epidemiological and laboratory findings

AV Skalny, M Aschner, EV Silina, VA Stupin… - Biomolecules, 2023 - mdpi.com
The objective of the present study was to review recent epidemiological and clinical data on
the association between selected minerals and trace elements and osteoporosis, as well as …