Modern medicine has been waging a war on cancer for nearly a century with no tangible
end in sight. Cancer treatments have significantly progressed, but the need to increase …

Head and neck cancer is a common and aggressive malignancy with a high morbidity and
mortality profile. Although the large majority of cases resemble head and neck squamous …

It is verified that failure in cancer therapy by conventional chemotherapeutic agents arise
from cancer heterogeneity. That, a small subpopulation of cancer cells known as “cancer …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most commonly diagnosed
cancer worldwide. Despite advances in the treatment management, locally advanced …

Current cancer therapies target the bulk of the tumour, while a population of highly resistant
tumour cells may be able to repopulate the tumour and metastasize to new sites. Cancer …

The inefficient tumor penetration of therapeutic antibodies has hampered their effective use
in treating solid tumors. Here, we report the identification of a fully human single-domain …

Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive tumor and the
sixth most common cancer worldwide. Current treatment strategies for HNSCC are surgery …

Preclinical animal models of oral squamous cell carcinoma (OSCC) have been extensively
studied in recent years. Investigating the pathogenesis and potential therapeutic strategies …

Antibody–drug conjugates (ADCs) are a class of biopharmaceuticals that combine the
specificity of antibodies with the high-potency of cytotoxic drugs. Engineering cysteine …

Oral squamous cell carcinoma (SCC) represents a major worldwide disease burden, with
high rates of recurrence and metastatic spread following existing treatment methods …