Application of the nano-drug delivery system in treatment of cardiovascular diseases

Y Deng, X Zhang, H Shen, Q He, Z Wu… - … in bioengineering and …, 2020 - frontiersin.org
Cardiovascular diseases (CVDs) have become a serious threat to human life and health.
Though many drugs acting via different mechanism of action are available in the market as …

[HTML][HTML] Structural and temporal dynamics analysis on drug-eluting stents: history, research hotspots and emerging trends

L Tan, X Wang, K Yuan, T Yin, R Du, L Shen, Z Zhu… - Bioactive Materials, 2023 - Elsevier
Purpose This review aims to explore the history, research hotspots, and emerging trends of
drug-eluting stents (DES) in the last two decades from the perspective of structural and …

Surface modification to enhance cell migration on biomaterials and its combination with 3D structural design of occluders to improve interventional treatment of heart …

Y Shen, W Zhang, Y Xie, A Li, X Wang, X Chen, Q Liu… - Biomaterials, 2021 - Elsevier
The dominant source of thromboembolism in heart comes from the left atrial appendage
(LAA). An occluder can close LAA and significantly reduce the risk of strokes, particularly for …

Core/shell piezoelectric nanofibers with spatial self-orientated β-phase nanocrystals for real-time micropressure monitoring of cardiovascular walls

T Li, ZQ Feng, M Qu, K Yan, T Yuan, B Gao, T Wang… - ACS …, 2019 - ACS Publications
Implantable pressure biosensors show great potential for assessment and diagnostics of
pressure-related diseases. Here, we present a structural design strategy to fabricate …

In-stent restenosis after percutaneous coronary intervention: emerging knowledge on biological pathways

F Pelliccia, M Zimarino, G Niccoli… - … Heart Journal Open, 2023 - academic.oup.com
Percutaneous coronary intervention (PCI) has evolved significantly over the past four
decades. Since its inception, in-stent restenosis (ISR)—the progressive reduction in vessel …

Multilevel assessment of stent-induced inflammation in the adjacent vascular tissue

K Kapnisis, A Stylianou, D Kokkinidou… - ACS Biomaterials …, 2023 - ACS Publications
A recent US Food and Drug Administration report presented the currently available scientific
information related to biological response to metal implants. In this work, a multilevel …

Micelle-embedded layer-by-layer coating with catechol and phenylboronic acid for tunable drug loading, sustained release, mild tissue response, and selective cell …

J Lu, W Zhuang, L Li, B Zhang, L Yang… - … applied materials & …, 2019 - ACS Publications
Tunable/sustained drug loading/releasing are of significance in addressing low cytotoxicity,
long-term performance, and localized mild healing response in biomedical applications …

In-stent restenosis progression in human superficial femoral arteries: dynamics of lumen remodeling and impact of local hemodynamics

M Colombo, Y He, A Corti, D Gallo, F Ninno… - Annals of Biomedical …, 2021 - Springer
In-stent restenosis (ISR) represents a major drawback of stented superficial femoral arteries
(SFAs). Motivated by the high incidence and limited knowledge of ISR onset and …

Disturbed flow's impact on cellular changes indicative of vascular aneurysm initiation, expansion, and rupture: A pathological and methodological review

K Sunderland, J Jiang, F Zhao - Journal of cellular physiology, 2022 - Wiley Online Library
Aneurysms are malformations within the arterial vasculature brought on by the structural
breakdown of the microarchitecture of the vessel wall, with aneurysms posing serious health …

[HTML][HTML] Photo-functionalized TiO2 nanotubes decorated with multifunctional Ag nanoparticles for enhanced vascular biocompatibility

J Chen, S Dai, L Liu, MF Maitz, Y Liao, J Cui, A Zhao… - Bioactive Materials, 2021 - Elsevier
Titanium dioxide (TiO 2) has a long history of application in blood contact materials, but it
often suffers from insufficient anticoagulant properties. Recently, we have revealed the …