Gallic acid for cancer therapy: Molecular mechanisms and boosting efficacy by nanoscopical delivery

M Ashrafizadeh, A Zarrabi, S Mirzaei, F Hashemi… - Food and Chemical …, 2021 - Elsevier
Cancer is the second leading cause of death worldwide. Majority of recent research efforts in
the field aim to address why cancer resistance to therapy develops and how to overcome or …

Gallic acid: A dietary polyphenol that exhibits anti-neoplastic activities by modulating multiple oncogenic targets

HS Tuli, H Mistry, G Kaur, D Aggarwal… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Phytochemicals are being used for thousands of years to prevent dreadful malignancy. Side
effects of existing allopathic treatment have also initiated intense research in the field of …

Interplay between male reproductive system dysfunction and the therapeutic effect of flavonoids

RJ Ye, JM Yang, DM Hai, N Liu, L Ma, XB Lan, JG Niu… - Fitoterapia, 2020 - Elsevier
Male infertility has affected many families around the world. However, due to the mechanism
underlying male reproductive system dysfunction are not completely elucidated, the use of …

Antioxidant and antitumoral activities of isolated macamide and macaene fractions from Lepidium meyenii (Maca)

L Fu, J Wei, Y Gao, R Chen - Talanta, 2021 - Elsevier
In this paper, a UPLC-ESI-MS was established to analyze macamide and macaene fractions
from Lepidium meyenii (Maca). The antioxidant activity of Maca crude extract (MCE), total …

The relationship between sperm oxidative stress alterations and IVF/ICSI outcomes: a systematic review from nonhuman mammals

J Ribas-Maynou, M Yeste, A Salas-Huetos - Biology, 2020 - mdpi.com
Achieving high embryo quality following IVF and ICSI procedures is a key factor in
increasing fertility outcomes in human infertile couples. While the male factor is known to …

Uncovering the mechanism of the effects of Paeoniae Radix Alba on iron-deficiency anaemia through a network pharmacology-based strategy

X Ye, Y Deng, L Xia, H Ren, J Zhang - BMC complementary medicine and …, 2020 - Springer
Abstract Background Paeoniae Radix Alba, the root of the plant Paeonia lactiflora Pall, is a
common blood-enriching drug in traditional Chinese medicine. Its effectiveness in the …

Evaluation of supplementation of cryopreservation medium with gallic acid as an antioxidant in quality of post‐thaw human spermatozoa

M Akbarzadeh‐Jahromi, F Jafari, ME Parsanezhad… - Andrologia, 2022 - Wiley Online Library
Human sperm cryopreservation is a way to preserve sperm in the clinic. But, the production
of reactive oxygen species (ROS) during cryopreservation, has certain negative impacts on …

[HTML][HTML] The effect of hydro-alcoholic extract of Ceratonia Silique L. on spermatogenesis index in rats treated with cyclophosphamide: An experimental study

F Sadeghzadeh, A Sadeghzadeh… - International Journal …, 2020 - ncbi.nlm.nih.gov
Background The aim of this study was to investigate the antioxidant effects of Ceratonia
extract on improving the toxicity induced by cyclophosphamide (CP) on spermatogenesis …

Flavonoids as potential therapeutics in male reproductive disorders

R Mishra, A Nikam, J Hiwarkar, T Nandgude… - Future Journal of …, 2024 - Springer
Background Male infertility presents global challenges, as current drug-based treatments
demonstrate limited effectiveness due to an incomplete understanding of dysfunctions within …

An Integrated analysis of network pharmacology, molecular docking, and experiment validation to explore the new candidate active component and mechanism of …

X Bai, Y Tang, Q Li, D Liu, G Liu, X Fan… - Drug Design …, 2021 - Taylor & Francis
Purpose One of the most common types of male infertility is recognized as
oligoasthenozoospermia (OA), characterized by low sperm count and quality in males. As a …