The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …

A novel series of ketohydrazide-hydrazones as analogues of naturally occurring
coscinamides has been synthesized and evaluated for their anticancer activity against five …

A series of substituted benzimidazoles were efficiently prepared by combining 1, 2-
phenylenediamine with aryl, heteroaryl aldehydes in the presence of catalytic amount of …

As the rate of discovery of new antibacterial compounds for multidrug-resistant bacteria is
declining, there is an urge for the search for molecules that could revert this tendency …

N-Alkylated benzimidazole derivatives have been synthesized via the aza-Michael addition
reactions of 1H-benzimidazoles to α, β-unsaturated compounds in water and palladium …

An efficient one-pot, two-step procedure has been successfully applied for the synthesis of a
series of 2-(5-phenylindol-3-yl) benzimidazoles. The first step was cyclocondensation …

Bacterial cell division requires identification of the division site, assembly of the division
machinery, and constriction of the cell envelope. These processes are regulated in response …

Ferroptosis is a cell death event caused by increased lipid peroxidation leading to iron‐
dependent oxidative stress and is associated with a wide variety of diseases. In recent …

Benzimidazole scaffolds became an attractive subject due to their broad spectrum of
pharmacological activities. In this work, a methodology was developed for the synthesis of N …

Glutathione peroxidases (GPx) were the first selenocysteine enzymes identified. They play
critical roles in cellular defense to excess H _ 2 O _ 2 H 2 O 2 and lipid peroxides, with GPx1 …