Plant byproducts and waste present enormous environmental challenges and an
opportunity for valorization and industrial application. Due to consumer demands for natural …

The species Fissistigma oldhamii (Hemsl.) Merr.(Annonaceae) has long been used as a
traditional herbal medicine in China to treat diverse human diseases. Decoctions from the …

Fatty acid synthases (FASs) and polyketide synthases (PKSs) iteratively elongate and often
reduce two-carbon ketide units in de novo fatty acid and polyketide biosynthesis. Cycles of …

Sapindus saponins extracted from S. mukorossi have been reported to exert antibacterial
activities against skin pathogenic bacteria, but their antibacterial mechanism is still at an …

Staphylococcus aureus infection is a leading cause of mortality and morbidity in community,
hospital and live-stock sectors, especially with the widespread emergence of methicillin …

摘要II 型脂肪酸合成途径(FAS-II) 是细菌和植物体内进行饱和/不饱和脂肪酸合成的唯一必需途径
. FAS-II 由一系列单一基因编码的可溶性酶组成, 通过依次循环式的识别和催化由酰基载体蛋白 …

One of the global challenges of the 21st century is the increase in mortality from infectious
diseases against the backdrop of the spread of antibiotic-resistant pathogenic …

Type-Ⅱ fatty acid biosynthesis pathway (FAS-Ⅱ) is the only essential biosynthesis pathway
that producing saturated and unsaturated fatty acids for bacteria and plant cell assembly and …

The fatty acid biosynthesis (FAS II) is a vital process in bacteria and regarded as an
attractive pathway for the development of potential antimicrobial agents. In this study, we …

The enoyl-acyl carrier protein reductase (ENR) is an established drug target and catalyzes
the last reduction step of the fatty acid elongation cycle. Here, we report the crystal structures …