The aim of the present review paper is to survey the literature related to DNA methylation,
and its association with cancer and ageing. The review will outline the key factors, including …

TET2, a member of ten-eleven translocation (TET) family as α-ketoglutarate-and Fe2+-
dependent dioxygenase catalyzing the iterative oxidation of 5-methylcytosine (5mC), has …

Modern lifestyle, genetics, nutritional overload through high-fat diet attributed prevalence
and diabetes outcomes with various complications primarily due to obesity in which energy …

Non-human primates are attractive laboratory animal models that accurately reflect both
developmental and pathological features of humans. Here we present a compendium of cell …

Transcription factors directly regulate gene expression by recognizing and binding to
specific DNA sequences, involving the dynamic alterations of chromatin structure and the …

Lines of evidence have shown the embryogenic and transgenerational impact of bisphenol
A (BPA), an endocrine-disrupting chemical, on immune-metabolic alterations, inflammation …

Asthma is a complex condition resulting from the interaction of genes and environment.
Obesity is a risk factor to develop asthma and contributes to poor response to asthma …

Edematous severe acute childhood malnutrition (edematous SAM or ESAM), which includes
kwashiorkor, presents with more overt multi-organ dysfunction than non-edematous SAM …

Failure to expand pancreatic β-cells in response to metabolic stress leads to excessive
workload resulting in β-cell dysfunction, dedifferentiation, death, and development of type 2 …

The pharmacoepigenetic apparatus is integrated by gene clusters of different categories,
including (i) pathogenic genes involved in disease pathogenesis,(ii) mechanistic genes …