Inhibition of glycolysis in the presence of antigen generates suppressive antigen-specific responses and restrains rheumatoid arthritis in mice
Dendritic cells (DCs) rely on glycolysis for their energy needs to induce pro-inflammatory
antigen-specific immune responses. Therefore, inhibiting DC glycolysis, while presenting …
antigen-specific immune responses. Therefore, inhibiting DC glycolysis, while presenting …
Coccidioidomycosis: changing concepts and knowledge gaps
NM Ampel - Journal of Fungi, 2020 - mdpi.com
Although first described more than 120 years ago, much remains unknown about
coccidioidomycosis. In this review, new information that has led to changing concepts will be …
coccidioidomycosis. In this review, new information that has led to changing concepts will be …
Database-assisted globally optimized targeted mass spectrometry (dGOT-MS): broad and reliable metabolomics analysis with enhanced identification
Targeted mass spectrometry (MS) is an important measurement approach in metabolomics
with strong analytical performance, given its specificity, sensitivity, and quantitative capacity …
with strong analytical performance, given its specificity, sensitivity, and quantitative capacity …
Triple negative breast cancer detection using LC–MS/MS lipidomic profiling
Breast cancer (BC) is a heterogeneous malignancy that is responsible for a great portion of
female cancer cases and cancer-related deaths in the United States. In comparison to other …
female cancer cases and cancer-related deaths in the United States. In comparison to other …
Metabolomic signatures of autism spectrum disorder
Autism Spectrum Disorder (ASD) is associated with many variations in metabolism, but the
ex-act correlates of these metabolic disturbances with behavior and development and their …
ex-act correlates of these metabolic disturbances with behavior and development and their …
Enhanced detection of short‐chain fatty acids using gas chromatography mass spectrometry
Short‐chain fatty acids (SCFAs) are produced mainly by intestinal microbiota and play an
important role in many host biological processes such as immune system development …
important role in many host biological processes such as immune system development …
Neuroinflammatory and neurometabolomic consequences from inhaled wildfire smoke-derived particulate matter in the Western United States
D Scieszka, R Hunter, J Begay, M Bitsui… - Toxicological …, 2022 - academic.oup.com
Utilizing a mobile laboratory located> 300 km away from wildfire smoke (WFS) sources, this
study examined the systemic immune response profile, with a focus on neuroinflammatory …
study examined the systemic immune response profile, with a focus on neuroinflammatory …
[HTML][HTML] Hypoxia promotes erythroid differentiation through the development of progenitors and proerythroblasts
Highlights•Low oxygen influences multiple stages in erythroid development.•Hypoxia
enhances the development of megakaryoerythroid progenitors and proerythroblasts.• …
enhances the development of megakaryoerythroid progenitors and proerythroblasts.• …
Comprehensive isotopic targeted mass spectrometry: reliable metabolic flux analysis with broad coverage
Metabolic flux analysis (MFA) is highly relevant to understanding metabolic mechanisms of
various biological processes. While the pace of methodology development in MFA has been …
various biological processes. While the pace of methodology development in MFA has been …
Central nervous system metabolism in autism, epilepsy and developmental delays: a cerebrospinal fluid analysis
D Brister, BA Werner, G Gideon, PJ McCarty, A Lane… - Metabolites, 2022 - mdpi.com
Neurodevelopmental disorders are associated with metabolic pathway imbalances;
however, most metabolic measurements are made peripherally, leaving central metabolic …
however, most metabolic measurements are made peripherally, leaving central metabolic …