The various types of biosensors such as enzyme-based, tissue-based, immunosensors,
DNA biosensors, thermal and piezoelectric biosensors have been deliberated here to …

Communication of molecular species through dynamic association and/or dissociation at
various cellular sites governs biological functions. Understanding these physiological …

Commonly used monomeric blue fluorescent proteins suffer from moderate brightness. The
brightest of them, mTagBFP, has a notably low chemical stability over time. Prolonged …

The functional state of a cell is largely determined by the spatiotemporal organization of its
proteome. Technologies exist for measuring particular aspects of protein turnover and …

Gene expression in multiple individual cells from a tissue or culture sample varies according
to cell-cycle, genetic, epigenetic and stochastic differences between the cells. However …

Multicolor imaging based on genetically encoded fluorescent proteins (FPs) is a powerful
approach to study several dynamic processes in a live cell. We report a monomeric orange …

Recent progress of bioanalytical techniques has accelerated the deep understanding of
cellular states and development of novel drugs as well as medical diagnosis. Particularly …

Background Our understanding of developmental processes relies fundamentally on their in
vivo observation. Morphogenesis, the shaping of an organism by cell movements, cell-cell …

Near-infrared light is favourable for imaging in mammalian tissues due to low absorbance of
hemoglobin, melanin, and water. Therefore, fluorescent proteins, biosensors and …

Skin‐deep: The combination of a near‐infrared fluorescent protein (iRFP) and deep‐tissue
photoacoustic tomography clearly demonstrates the superiority of iRFP over other …