Can regenerative medicine and nanotechnology combine to heal wounds? The search for the ideal wound dressing

P Zarrintaj, AS Moghaddam, S Manouchehri… - …, 2017 - Taylor & Francis
Skin is the outermost covering of the human body and at the same time the largest organ
comprising 15% of body weight and 2 m2 surface area. Skin plays a key role as a barrier …

Polymer nanomaterials for use as adjuvant surgical tools

M Erdi, A Sandler, P Kofinas - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
Materials employed in the treatment of conditions encountered in surgical and clinical
practice frequently face barriers in translation to application. Shortcomings can be …

Matricellular proteins in cutaneous wound healing

CG Cárdenas-León, K Mäemets-Allas… - Frontiers in Cell and …, 2022 - frontiersin.org
Cutaneous wound healing is a complex process that encompasses alterations in all aspects
of the skin including the extracellular matrix (ECM). ECM consist of large structural proteins …

Targeting OLFML3 in colorectal cancer suppresses tumor growth and angiogenesis, and increases the efficacy of anti-PD1 based immunotherapy

J Stalin, BA Imhof, O Coquoz, R Jeitziner, P Hammel… - Cancers, 2021 - mdpi.com
Simple Summary Tumor vascularization promotes tumor growth and is intimately connected
to immune system function. Despite efforts to use antiangiogenic therapies, their clinical …

Olfactomedin‐like 3 promotes PDGF‐dependent pericyte proliferation and migration during embryonic blood vessel formation

BA Imhof, R Ballet, P Hammel, S Jemelin… - The FASEB …, 2020 - Wiley Online Library
Pericytes promote vessel stability and their dysfunction causes pathologies due to blood
vessel leakage. Previously, we reported that Olfactomedin‐like 3 (Olfml3) is a matricellular …

Amorphous silk fibroin nanofiber hydrogels with enhanced mechanical properties

J Liu, Z Ding, G Lu, J Wang, L Wang… - Macromolecular …, 2019 - Wiley Online Library
Silk fibroin (SF) hydrogels have been engineered as universal substrates for various tissue
regenerations and drug delivery. Although different physical and chemical crosslinking …

A self-assembled peptide hydrogel for wound repair

C Cai, Z Meng, L Zhao, T Wu, X Xu, Y Zhu - Journal of Materials Science, 2022 - Springer
The skin is an important protective barrier for human. The epithelial barrier is destroyed
following a skin injury, thereby increasing the susceptibility of bacterial infections. After the …

Olfactomedin-like 3: possible functions in embryonic development and tumorigenesis

Y Jin, JL Li - Chinese Medical Journal, 2019 - journals.lww.com
Objective: Modern medical research has proven that human diseases are directly or
indirectly related to genes. At the same time, genetic research has also brought updates to …

Osteophyte Cartilage as a Potential Source for Minced Cartilage Implantation: A Novel Approach for Articular Cartilage Repair in Osteoarthritis

S Kawabata, T Nakasa, A Nekomoto, D Yimiti… - International Journal of …, 2024 - mdpi.com
Osteoarthritis (OA) is a common joint disorder characterized by cartilage degeneration, often
leading to pain and functional impairment. Minced cartilage implantation (MCI) has emerged …

Skin tissue engineering: biological performance of electrospun polymer scaffolds and translational challenges

KM Kennedy, A Bhaw-Luximon, D Jhurry - Regenerative Engineering and …, 2017 - Springer
Skin tissue engineering for wound healing requires a biomimetic scaffold that provides a
physical, chemical, and biological environment to guide cells toward regeneration. The …