RNA-binding proteins (RBPs) are essential for the development and function of the immune
system. They interact dynamically with RNA to control its biogenesis and turnover by …

Polypyrimidine tract-binding protein 1 (PTBP1) plays an essential role in splicing and is
expressed in almost all cell types in humans, unlike the other proteins of the PTBP family …

Polypyrimidine tract‐binding protein (PTB), as a member of the heterogeneous nuclear
ribonucleoprotein family, functions by rapidly shuttling between the nucleus and the …

Fighting external pathogens requires an ever-changing immune system that relies on tight
regulation of gene expression. Transcriptional control is the first step to build efficient …

Lentiviral‐vector‐based therapies, widely used for treating various diseases, face limitations
because of release burst, rapid clearance, and immune activation. Herein, a lentiviral vector …

Antibody affinity maturation occurs in germinal centers (GCs), where B cells cycle between
the light zone (LZ) and the dark zone. In the LZ, GC B cells bearing immunoglobulins with …

Polypyrimidine tract‑binding protein 1 (PTBP1) plays an important role in tumor immunity,
cell proliferation, apoptosis, and autophagy by regulating RNA metabolism. However, the …

The human immune response is a complex process that responds to numerous exogenous
antigens in preventing infection by microorganisms, as well as to endogenous components …

Polypyrimidine tract-binding protein 1 (PTBP1) is a RNA-binding protein (RBP) expressed
throughout B cell development. Deletion of Ptbp1 in mouse pro-B cells results in …

Abstract Polypyrimidine Tract-Binding Protein 1 (PTBP1) is an essential RNA-binding
protein that regulates diverse biological events through regulating alternative splice of …