Aims: Alpha-2-macroglobulin (α2 MG) is thought to be associated with inflammatory
reactions and procoagulant properties that might cause ischemic stroke. Endothelial …

Abstract Objective α2-macroglobulin (α2M) is an acute phase protein released to the serum
upon challenges such as cardiac hypertrophy and infarction. Here we report on the role of …

The physiological cardiac hypertrophy is an adaptive condition without myocyte cell death,
while pathological hypertrophy is a maladaptive condition associated with myocyte cell …

OBJECTIVE: Despite the number of potential biomarker proteins for diabetes, very few of
them have proven useful as clinically beneficial indicators, because of the technical …

Heavy metal exposure in children has been associated with a variety of physiological and
neurological problems. The goal of this study was to utilize proteomics to enhance the …

A2M is a broad spectrum proteinase inhibitor and cytokine carrier, besides presenting anti-
apoptotic activity through the binding to its receptor, LRP. During Trypanosoma cruzi …

Background Aortic aneurysm is an increasingly common vascular disorder with fatal
implication. However, there is no established diagnosis other than that based on …

Background Myocardin (MYOCD), a potent transcriptional coactivator of smooth muscle
(SM) and cardiac genes, is upregulated in failing myocardium in animal models and human …

BACKGROUND: Cardiac isoform of alpha 2 macroglobulin (CA2M), a serum protein
(182000Mr) has been used as a diagnostic molecular marker for cardiac manifestations in …

This study investigated the possible role of the cardiac isoform of alpha 2-macroglobulin
(CA2M) as an early diagnostic marker for HIV-associated cardiovascular manifestations. A …