Circulating nucleic acids (CNAs) and cancer—a survey

M Fleischhacker, B Schmidt - Biochimica et Biophysica Acta (BBA)-Reviews …, 2007 - Elsevier
It has been known for decades that it is possible to detect small amounts of extracellular
nucleic acids in plasma and serum of healthy and diseased human beings. The unequivocal …

Colorectal cancer biomarkers: where are we now?

M Gonzalez-Pons… - BioMed research …, 2015 - Wiley Online Library
Colorectal cancer is one of the major causes of cancer‐related death in the Western world.
Patient survival is highly dependent on the tumor stage at the time of diagnosis. Reduced …

Blood markers for early detection of colorectal cancer: a systematic review

S Hundt, U Haug, H Brenner - Cancer Epidemiology Biomarkers & …, 2007 - AACR
Background: Despite different available methods for colorectal cancer (CRC) screening and
their proven benefits, morbidity, and mortality of this malignancy are still high, partly due to …

Molecular tests for colorectal cancer screening

LJW Bosch, B Carvalho, RJA Fijneman… - Clinical colorectal …, 2011 - Elsevier
Detecting and removing high-risk adenomas and early colorectal cancer (CRC) can reduce
mortality of this disease. The noninvasive fecal occult blood test (FOBT; guaiac-based or …

Circulating nucleic acids as a potential source for cancer biomarkers

VV Vlassov, PP Laktionov… - Current molecular …, 2010 - ingentaconnect.com
Since the association of circulating DNA level changes with tumor growth was discovered
many attempts have been made to develop the sensitive and robust blood-based tests for …

[HTML][HTML] Telomeres, telomerase and colorectal cancer

R Bertorelle, E Rampazzo, S Pucciarelli… - World journal of …, 2014 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common cancer worldwide and, despite improved
treatments, is still an important cause of cancer-related deaths. CRC encompasses a …

[HTML][HTML] The combination of circulating long noncoding RNAs AK001058, INHBA-AS1, MIR4435-2HG, and CEBPA-AS1 fragments in plasma serve as diagnostic …

D Ke, H Li, Y Zhang, Y An, H Fu, X Fang, X Zheng - Oncotarget, 2017 - ncbi.nlm.nih.gov
The combination of circulating long noncoding RNAs AK001058, INHBA-AS1, MIR4435-2HG,
and CEBPA-AS1 fragments in plasma serve as diagnostic markers for gastric cancer - PMC …

Circulating nucleic acids in plasma and serum (CNAPS): applications in oncology

JA González-Masiá, D García-Olmo… - OncoTargets and …, 2013 - Taylor & Francis
The presence of small amounts of circulating nucleic acids in plasma and serum (CNAPS) is
not a new finding. The verification that such amounts are significantly increased in cancer …

Molecular detection of circulating tumor cells in the peripheral blood of patients with colorectal cancer using RT-PCR: significance of the prediction of postoperative …

JY Wang, CH Wu, CY Lu, JS Hsieh, DC Wu… - World journal of …, 2006 - Springer
Abstract Background Approximately 20%–45% of colorectal cancer (CRC) patients
ultimately develop local recurrence or metastasis following curative surgical resection. The …

[HTML][HTML] Circulating MACC1 transcripts in colorectal cancer patient plasma predict metastasis and prognosis

U Stein, S Burock, P Herrmann, I Wendler… - PloS one, 2012 - journals.plos.org
Background Metastasis is the most frequent cause of treatment failure and death in
colorectal cancer. Early detection of tumors and metastases is crucial for improving …