G protein-coupled receptors in taste physiology and pharmacology

R Ahmad, JE Dalziel - Frontiers in pharmacology, 2020 - frontiersin.org
Heterotrimeric G protein-coupled receptors (GPCRs) comprise the largest receptor family in
mammals and are responsible for the regulation of most physiological functions. Besides …

[HTML][HTML] Playing hide and seek with poorly tasting paediatric medicines: do not forget the excipients

J Walsh, A Cram, K Woertz, J Breitkreutz… - Advanced drug delivery …, 2014 - Elsevier
The development of paediatric medicines can be challenging since this is a diverse patient
population with specific needs. For example, the toxicity of excipients may differ in children …

Pharmaceutical cocrystals, salts and polymorphs: Advanced characterization techniques

E Pindelska, A Sokal, W Kolodziejski - Advanced drug delivery reviews, 2017 - Elsevier
The main goal of a novel drug development is to obtain it with optimal physiochemical,
pharmaceutical and biological properties. Pharmaceutical companies and scientists modify …

Fast disintegrating tablets: Opportunity in drug delivery system

V Parkash, S Maan, SK Yadav… - Journal of advanced …, 2011 - journals.lww.com
Fast disintegrating tablets (FDTs) have received ever-increasing demand during the last
decade, and the field has become a rapidly growing area in the pharmaceutical industry …

Taste sensing systems (electronic tongues) for pharmaceutical applications

K Woertz, C Tissen, P Kleinebudde… - International journal of …, 2011 - Elsevier
Electronic tongues are sensor array systems able to detect single substances as well as
complex mixtures by means of particular sensor membranes and electrochemical …

Adsorption and thermodynamic study of Cephalosporins antibiotics from aqueous solution onto MgO nanoparticles

A Fakhri, S Adami - Journal of the Taiwan Institute of Chemical Engineers, 2014 - Elsevier
The adsorption characteristics of Cephalosporins antibiotics from aqueous solution were
investigated using magnesium oxide (MgO) nanoparticles. Liquid phase adsorption …

Physical approaches to masking bitter taste: lessons from food and pharmaceuticals

JN Coupland, JE Hayes - Pharmaceutical research, 2014 - Springer
Many drugs and desirable phytochemicals are bitter, and bitter tastes are aversive. Food
and pharmaceutical manufacturers share a common need for bitterness-masking strategies …

Industry-relevant approaches for minimising the bitterness of bioactive compounds in functional foods: a review

D Sun-Waterhouse, SS Wadhwa - Food and Bioprocess Technology, 2013 - Springer
Functional foods, with their synergistic health benefits that go beyond just being a source of
individual nutrients, present challenges to the traditional 'nutrition'view of foods. Consumers …

pH-sensitive polymers for drug delivery

KM Huh, HC Kang, YJ Lee, YH Bae - Macromolecular research, 2012 - Springer
Various pH-sensitive polymers have been developed for biomedical applications and
recently attracted much attention for pH targeting nanomedicine. Recent development of pH …

Development of a taste-masked orodispersible film containing dimenhydrinate

M Preis, M Pein, J Breitkreutz - Pharmaceutics, 2012 - mdpi.com
Orodispersible dosage forms are promising new approaches for drug delivery. They enable
an easy application, as there is no need to drink high amounts of liquids or swallow large …