Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention

B Yilmaz, H Terekeci, S Sandal… - Reviews in endocrine and …, 2020 - Springer
Abstract Endocrine Disrupting Chemicals (EDCs) are a global problem for environmental
and human health. They are defined as “an exogenous chemical, or mixture of chemicals …

Potential mechanisms of bisphenol A (BPA) contributing to human disease

I Cimmino, F Fiory, G Perruolo, C Miele… - International journal of …, 2020 - mdpi.com
Bisphenol A (BPA) is an organic synthetic compound serving as a monomer to produce
polycarbonate plastic, widely used in the packaging for food and drinks, medical devices …

Re‐evaluation of the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs

EFSA Panel on Food Contact Materials … - EFSA …, 2023 - Wiley Online Library
In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body
weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the …

[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

To waste or not to waste: questioning potential health risks of micro-and nanoplastics with a focus on their ingestion and potential carcinogenicity

ES Gruber, V Stadlbauer, V Pichler… - Exposure and …, 2023 - Springer
Micro-and nanoplastics (MNPs) are recognized as emerging contaminants, especially in
food, with unknown health significance. MNPs passing through the gastrointestinal tract …

Human exposure to endocrine disrupting compounds: Their role in reproductive systems, metabolic syndrome and breast cancer. A review

M Giulivo, ML de Alda, E Capri, D Barceló - Environmental research, 2016 - Elsevier
Endocrine disrupting chemicals (EDCs) are released into the environment from different
sources. They are mainly used in packaging industries, pesticides and food constituents …

Obesity, diabetes, and associated costs of exposure to endocrine-disrupting chemicals in the European Union

J Legler, T Fletcher, E Govarts, M Porta… - The Journal of …, 2015 - academic.oup.com
Context: Obesity and diabetes are epidemic in the European Union (EU). Exposure to
endocrine-disrupting chemicals (EDCs) is increasingly recognized as a contributor …

Endocrine-disrupting chemicals and the regulation of energy balance

A Nadal, I Quesada, E Tuduri, R Nogueiras… - Nature Reviews …, 2017 - nature.com
Energy balance involves the adjustment of food intake, energy expenditure and body fat
reserves through homeostatic pathways. These pathways include a multitude of biochemical …

Endocrine-disrupting chemicals and risk of diabetes: an evidence-based review

PM Lind, L Lind - Diabetologia, 2018 - Springer
The purpose of this study was to review the epidemiological and experimental evidence
linking background exposure to a selection of environmental endocrine-disrupting …