Design, synthesis, and biological evaluation of SSE1806, a microtubule destabilizer that overcomes multidrug resistance
Microtubules are dynamic structures that form spindle fibers during cell division;
pharmacological inhibition of microtubule dynamics arrests cells in mitosis, leading to …
pharmacological inhibition of microtubule dynamics arrests cells in mitosis, leading to …
Synthesis, Biological and In Silico Studies of Griseofulvin and Usnic Acid Sulfonamide Derivatives as Fungal, Bacterial and Human Carbonic Anhydrase Inhibitors
A Angeli, A Petrou, V Kartsev, B Lichitsky… - International Journal of …, 2023 - mdpi.com
Carbonic anhydrases (CAs, EC 4.2. 1.1) catalyze the essential reaction of CO2 hydration in
all living organisms, being actively involved in the regulation of a plethora of patho …
all living organisms, being actively involved in the regulation of a plethora of patho …
Synthesis and characterization of bis-amide SSE1917 as a microtubule-stabilizing anticancer agent
Microtubule dynamics are critical for spindle assembly and chromosome segregation during
cell division. Pharmacological inhibition of microtubule dynamics in cells causes prolonged …
cell division. Pharmacological inhibition of microtubule dynamics in cells causes prolonged …