Epitope-based vaccine design: a comprehensive overview of bioinformatics approaches
Highlights•Epitope vaccines provide maximal therapeutic efficacy with minimal side
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
Interferon‐alpha position in combating with COVID‐19: A systematic review
The newborn coronaivus disease 2019 (COVID‐19) pandemic has become the foremost
concern of health system worldwide. Interferon typeI (IFN‐I) are among the well‐known …
concern of health system worldwide. Interferon typeI (IFN‐I) are among the well‐known …
A domain-based vaccine construct against SARS-CoV-2, the causative agent of COVID-19 pandemic: development of self-amplifying mRNA and peptide vaccines
Introduction: Coronavirus disease 2019 (COVID-19) is undoubtedly the most challenging
pandemic in the current century with more than 293,241 deaths worldwide since its …
pandemic in the current century with more than 293,241 deaths worldwide since its …
Design of a Novel Multi-Epitope Vaccine Against Echinococcus granulosus in Immunoinformatics
M Yu, Y Zhu, Y Li, Z Chen, T Sha, Z Li, F Zhang… - Frontiers in …, 2021 - frontiersin.org
All the time, echinococcosis is a global zoonotic disease which seriously endangers public
health all over the world. In order to speed up the development process of anti …
health all over the world. In order to speed up the development process of anti …
[HTML][HTML] A multi-method and structure-based in silico vaccine designing against Echinococcus granulosus through investigating enolase protein
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Introduction: Hydatid disease is a ubiquitous parasitic zoonotic disease, which causes …
Introduction: Hydatid disease is a ubiquitous parasitic zoonotic disease, which causes …
Defeating a superbug: A breakthrough in vaccine design against multidrug-resistant Pseudomonas aeruginosa using reverse vaccinology
S Fereshteh, F Haririzadeh Jouriani… - PLoS …, 2023 - journals.plos.org
Background Multidrug-resistant Pseudomonas aeruginosa has become a major cause of
severe infections. Due to the lack of approved vaccines, this study has presented putative …
severe infections. Due to the lack of approved vaccines, this study has presented putative …
In silico design of a triple-negative breast cancer vaccine by targeting cancer testis antigens
Introduction: Triple-negative breast cancer (TNBC) is an important subtype of breast cancer,
which occurs in the absence of estrogen, progesterone and HER-2 receptors. According to …
which occurs in the absence of estrogen, progesterone and HER-2 receptors. According to …
A novel multi-objective metaheuristic algorithm for protein-peptide docking and benchmarking on the LEADS-PEP dataset
Protein-peptide interactions have attracted the attention of many drug discovery scientists
due to their possible druggability features on most key biological activities such as …
due to their possible druggability features on most key biological activities such as …
Towards a new avenue for producing therapeutic proteins: Microalgae as a tempting green biofactory
Most of the recent approved therapeutic proteins are multi-subunit biologics, which need
glycosylation and disulfide bridges for their correct conformation and biological functions …
glycosylation and disulfide bridges for their correct conformation and biological functions …
A novel B-and helper T-cell epitopes-based prophylactic vaccine against Echinococcus granulosus
MM Pourseif, G Moghaddam, H Daghighkia… - BioImpacts …, 2017 - pmc.ncbi.nlm.nih.gov
Introduction: In this study, we targeted the worm stage of Echinococcus granulosus to design
a novel multi-epitope B-and helper T-cell based vaccine construct for immunization of dogs …
a novel multi-epitope B-and helper T-cell based vaccine construct for immunization of dogs …