Cervical cancer is the third most common cancer in women worldwide, with concepts and
knowledge about its prevention and treatment evolving rapidly. Human papillomavirus …

Methodological breakthroughs over the past four decades have repeatedly revolutionized
transcriptome profiling. Using RNA sequencing (RNA-seq), it has now become possible to …

Hepatocellular carcinoma is the third leading cause of deaths from cancer worldwide.
Infection with the hepatitis B virus is one of the leading risk factors for developing …

Background RNA sequencing has become a ubiquitous technology used throughout life
sciences as an effective method of measuring RNA abundance quantitatively in tissues and …

The mutagenic effect of hepatitis B (HBV) integration in predisposing risk to hepatocellular
carcinoma (HCC) remains elusive. In this study, we performed transcriptome sequencing of …

Metagenomics poses opportunities for clinical and public health virology applications by
offering a way to assess complete taxonomic composition of a clinical sample in an …

Next generation sequencing (NGS) has revolutionized virus discovery. Notwithstanding, a
vertical pipeline, from sample preparation to data analysis, has not been available to the …

Next generation sequencing (NGS) technologies allow us to explore virus interactions with
host genomes that lead to carcinogenesis or other diseases; however, this effort is largely …

Chronic hepatitis B virus (HBV) infection remains the number one risk factor for
hepatocellular carcinoma (HCC), accounting for more than 600 000 deaths/year. Despite …

Exome sequencing is one of the most cost-efficient sequencing approaches for conducting
genome research on coding regions. However, significant portions of the reads obtained in …