The potential of cold-shock promoters for the expression of recombinant proteins in microbes and mammalian cells

Y Bartolo-Aguilar, C Chávez-Cabrera… - Journal of Genetic …, 2022 - Springer
Background Low-temperature expression of recombinant proteins may be advantageous to
support their proper folding and preserve bioactivity. The generation of expression vectors …

Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179

DN Patil, S Pantalone, Y Cao, T Laboute, SJ Novick… - Science …, 2023 - science.org
Precise synapse formation is essential for normal functioning of the nervous system. Retinal
photoreceptors establish selective contacts with bipolar cells, aligning the neurotransmitter …

A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis

D Pradella, G Deflorian, A Pezzotta, A Di Matteo… - Nature …, 2021 - nature.com
Abstract The Netrin-1 receptor UNC5B is an axon guidance regulator that is also expressed
in endothelial cells (ECs), where it finely controls developmental and tumor angiogenesis. In …

Recombinant fibrous protein biomaterials meet skin tissue engineering

D Li, Y Wang, S Zhu, X Hu, R Liang - Frontiers in Bioengineering and …, 2024 - frontiersin.org
Natural biomaterials, particularly fibrous proteins, are extensively utilized in skin tissue
engineering. However, their application is impeded by batch-to-batch variance, limited …

p38 MAPK involvement in the thermal stress response occurs via HSP27 and caspase3 in the large yellow croaker (Larimichthys crocea)

QJ Jia, CL Yao - Comparative Biochemistry and Physiology Part B …, 2024 - Elsevier
The p38 mitogen-activated protein kinase (p38 MAPK) is a multifunctional molecule that is
involved in cellular response to various stressful stimuli. In the present study, the full-length …

A pilot study on Covid and autism: prevalence, clinical presentation and vaccine side effects

N Brondino, F Bertoglio, F Forneris, S Faravelli… - Brain Sciences, 2021 - mdpi.com
Background: Several neurobiological mechanisms have been proposed to support the
hypothesis of a higher COVID-19 risk in individuals with autism spectrum disorder (ASD) …

Long-Term Culturing of FreeStyle 293-F Cells Affects Immunoglobulin G Glycome Composition

F Lukšić, A Mijakovac, G Josipović, V Vičić Bočkor… - Biomolecules, 2023 - mdpi.com
Glycosylation of IgG regulates the effector function of this antibody in the immune response.
Glycosylated IgG is a potent therapeutic used for both research and clinical purposes. While …

[HTML][HTML] Efficient SARS-CoV-2 infection antagonization by rhACE2 ectodomain multimerized onto the Avidin-Nucleic-Acid-NanoASsembly

S Bernardotto, I Frasson, S Faravelli, A Morelli… - Biomaterials, 2023 - Elsevier
Nanodecoy systems based on analogues of viral cellular receptors assembled onto fluid
lipid-based membranes of nano/extravescicles are potential new tools to complement …

New mechanistic insights to PLOD1-mediated human vascular disease

SN Koenig, O Cavus, J Williams, M Bernier… - Translational …, 2022 - Elsevier
Heritable thoracic aortic disease and familial thoracic aortic aneurysm/dissection are
important causes of human morbidity/mortality, most without identifiable genetic cause. In a …

[HTML][HTML] PVA/gelatin hydrogel loaded with propolis for the treatment of myocardial infarction

AI Pangesty, CS Dwinovandi, SJAP Tarigan… - Journal of Science …, 2024 - Elsevier
Recently, propolis has shown potential cardioprotective effects against myocardial infarction.
However, challenges in its clinical application have arisen, primarily due to concerns …