Mechanisms and the evidence hierarchy

B Clarke, D Gillies, P Illari, F Russo, J Williamson - Topoi, 2014 - Springer
Evidence-based medicine (EBM) makes use of explicit procedures for grading evidence for
causal claims. Normally, these procedures categorise evidence of correlation produced by …

Epistemology of causal inference in pharmacology: Towards a framework for the assessment of harms

J Landes, B Osimani, R Poellinger - European Journal for Philosophy of …, 2018 - Springer
Philosophical discussions on causal inference in medicine are stuck in dyadic camps, each
defending one kind of evidence or method rather than another as best support for causal …

What's in a gold standard? In defence of randomised controlled trials

M Backmann - Medicine, Health Care and Philosophy, 2017 - Springer
The standardised randomised clinical trial (RCT) has been exceedingly popular in medical
research, economics, and practical policy making. Recently, RCTs have faced criticism. First …

[图书][B] Taming randomized controlled trials in education: Exploring key claims, issues and debates

K Morrison - 2020 - taylorfrancis.com
There is a recent surge in the use of randomized controlled trials (RCTs) within education
globally, with disproportionate claims being made about what they show,'what works', and …

The confounding question of confounding causes in randomized trials

J Fuller - The British Journal for the Philosophy of Science, 2019 - journals.uchicago.edu
It is sometimes thought that randomized study group allocation is uniquely proficient at
producing comparison groups that are evenly balanced for all confounding causes …

Use and reporting of restricted randomization: a review

R Higham, P Tharmanathan… - Journal of evaluation in …, 2015 - Wiley Online Library
Rationale, aims and objectives Restricted randomization, such as blocking or minimization,
allows for the creation of balanced groups and even distribution of covariates, but it …

Epistemic gains and epistemic games: Reliability and higher order evidence in medicine and pharmacology

B Osimani - Uncertainty in Pharmacology, 2020 - library.oapen.org
In this paper I analyse the dissent around evidence standards in medicine and
pharmacology as a result of distinct ways to address epistemic losses in our game with …

Randomized controlled trials in the West African Ebola virus outbreak

R Upshur, J Fuller - Clinical Trials, 2016 - journals.sagepub.com
The Ebola virus outbreak in West Africa poses significant global health challenges. It marks
the first time in history that the Ebola virus, a level four pathogen, has gained a foothold in a …

Does randomization assert the balance across trial arms? Revisiting Worrall's criticism

M Maziarz - History and Philosophy of the Life Sciences, 2025 - Springer
Abstract We revisit John Worrall's old but still prominent argument against the view that
randomization balances the impact of both known and unknown confounders across the …

[PDF][PDF] Randomized trials and observational studies: the current philosophical controversy

J Howick, A Mebius - Handbook of the philosophy of medicine …, 2017 - academia.edu
Randomized Trials and Observational Studies: The Current Philosophical Controversy Page 1
Randomized Trials and Observational Studies: The Current Philosophical Controversy 53 …