Lipases have been well established as valuable catalysts in organic synthesis. This review
article focuses on some of the recent developments in the rapidly growing field of lipase …

Lipase-catalyzed kinetic resolution of racemates is considered to be one of the most
fascinating topics in asymmetric catalysis. This review focuses on some of the recent …

Glecaprevir was identified as a potent HCV NS3/4A protease inhibitor, and an enabling
synthesis was required to support the preclinical evaluation and subsequent Phase I clinical …

Kinetic resolutions of cyclic racemic secondary alcohols (2-methylenecyclopentan-1-ol rac-
1a, 2-methylenecyclohexan-1-ol rac-1b, 2-methylenecycloheptan-1-ol rac-1c, 6-methylene …

Two extracellular lipases from Bacillus subtilis, B. subtilis lipase A and lipase B, have been
expressed in the heterologous host Escherichia coli, biochemically characterized and used …

Chiral copper (II) coordination polymers 1a− c have been prepared by one-pot synthesis in
high yield. Their single-crystal X-ray analysis showed that repeating units are connected to …

We present an organocatalytic C–O-bond cross-coupling strategy to kinetically resolve
racemic diols with aromatic and aliphatic alcohols, yielding enantioenriched esters. This one …

A simple method for the resolution of racemic trans-1, 2-cyclohexanediol enantiomers is
presented in this paper. The chiral discrimination was performed by tartaric acid via …

Preparation of Polycarboxylic Acids by Oxidative Cleavage with Oxygen / Co–Mn–Br System
Page 1 1 INTRODUCTION Polycarboxylic acids, which are used as raw materials of lubricant …

Acetogenin analogs in which the bis-adjacent THF ring was replaced with an
enantioselectively synthesized 1, 2-cyclopentanediol bis-ether skeleton were synthesized to …