The role of the prefrontal cortex (PFC) takes center stage among unanswered questions in
modern neuroscience. The PFC has a Janus-faced nature: it enables sophisticated cognitive …

The synapse is the focus of experimental research and theory on the cellular mechanisms of
nervous system plasticity and learning, but recent research is expanding the consideration …

Relative to childhood, peer relationships take on a heightened importance during
adolescence. Might adolescents be highly attuned to information that concerns when and …

The number of patients surviving with congenital heart disease (CHD) has soared over the
last 3 decades. Adults constitute the fastest-growing segment of the CHD population, now …

Brains systems undergo unique and specific dynamic changes at the cellular, circuit, and
systems level that underlie the transition to adult-level cognitive control. We integrate …

This review article examines theoretical and methodological issues in the construction of a
developmental perspective on executive function (EF) in childhood and adolescence. Unlike …

Adolescence is a time in development when significant changes occur in affective
neurobiology. These changes provide a prolonged period of plasticity to prepare the …

White matter (WM) continues to mature through adolescence in parallel with gains in
cognitive ability. To date, developmental changes in human WM microstructure have been …

Background Adolescence is the phase of life between late childhood and adulthood.
Typically, adolescents seek diversion, new experiences, and strong emotions, sometimes …

This report calls on the nation—its leaders, its mental health research and service provision
agencies, its schools, its primary care medical systems, its community-based organizations …