A historical overview of peptide chemistry from T. Curtius to E. Fischer to M. Bergmann and
L. Zervas is first presented. Next, the fundamentals of peptide synthesis with a focus on solid …

The last decade has witnessed a renaissance of peptides as drugs. This progress, together
with advances in the structural behavior of peptides, has attracted the interest of the …

In response to the need for more sustainable practices in peptide synthesis, particularly in
the context of solid-phase peptide synthesis (SPPS), this study introduces a transformative …

Three novel glycine-rich peptides, named ctenidin 1–3, with activity against the Gram-
negative bacterium E. coli, were isolated and characterized from hemocytes of the spider …

Although glycine-rich antimicrobial peptides (AMPs) are found in animals and plants, very
little has been reported on their chemistry, structure activity-relationship, and properties. We …

Peptides are biomolecules that may have several biological activities which makes them
important to the environment in which they operate. Sometimes it is necessary for larger …

Several conditions have been used in the coupling reaction of stepwise SPPS at elevated
temperature (SPPS‐ET), but we have elected the following as our first choice: 2.5‐fold molar …

Iron overload causes progressive and sometimes irreversible damage due to accelerated
production of reactive oxygen species. Desferrioxamine (DFO), a siderophore, has been …

Chronic HBV infection is the leading cause of liver cirrhosis and hepatocellular carcinoma
(HCC). Synthetic peptides derived from the N-terminus of the large HBV envelope protein (L …

Peptides continue to arouse an impressive deal of interest in different areas of modern life.
In the last decades, special emphasis was placed on peptides capable of killing pathogenic …