Targeting cancer-promoting inflammation—have anti-inflammatory therapies come of age?
The immune system has crucial roles in cancer development and treatment. Whereas
adaptive immunity can prevent or constrain cancer through immunosurveillance, innate …
adaptive immunity can prevent or constrain cancer through immunosurveillance, innate …
Obesity and cancer risk: Emerging biological mechanisms and perspectives
Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …
Recommendations for follow-up after colonoscopy and polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer
S Gupta, D Lieberman, JC Anderson… - Official journal of the …, 2020 - journals.lww.com
Colonoscopy is performed routinely for colorectal cancer (CRC) screening, follow-up of
other abnormal screening tests, workup of signs and symptoms of gastrointestinal disease …
other abnormal screening tests, workup of signs and symptoms of gastrointestinal disease …
Is it still worth pursuing the repurposing of metformin as a cancer therapeutic?
Over the past 15 years, there has been great interest in the potential to repurpose the
diabetes drug, metformin, as a cancer treatment. However, despite considerable efforts …
diabetes drug, metformin, as a cancer treatment. However, despite considerable efforts …
The beneficial effects of metformin on cancer prevention and therapy: a comprehensive review of recent advances
Metformin is a widely used drug in today's prescriptions by physicians due to its specific
effects in treating and curing type II diabetes. Diabetes is a common disease that may occur …
effects in treating and curing type II diabetes. Diabetes is a common disease that may occur …
[HTML][HTML] Metformin as an adjuvant treatment for cancer: a systematic review and meta-analysis
C Coyle, FH Cafferty, C Vale, RE Langley - Annals of Oncology, 2016 - Elsevier
This systematic review and meta-analysis is the first to evaluate the evidence for an
association between metformin use and cancer outcomes in patients undergoing treatment …
association between metformin use and cancer outcomes in patients undergoing treatment …
Environmental factors, gut microbiota, and colorectal cancer prevention
The substantial burden of colorectal cancer and increasing trend in young adults highlight
the importance of lifestyle modification as a complement to screening for colorectal cancer …
the importance of lifestyle modification as a complement to screening for colorectal cancer …
Drug repurposing in cancer
L Sleire, HE Førde, IA Netland, L Leiss, BS Skeie… - Pharmacological …, 2017 - Elsevier
Cancer is a major health issue worldwide, and the global burden of cancer is expected to
increase in the coming years. Whereas the limited success with current therapies has driven …
increase in the coming years. Whereas the limited success with current therapies has driven …
Metformin as an anticancer agent
A Vancura, P Bu, M Bhagwat, J Zeng… - Trends in pharmacological …, 2018 - cell.com
Metformin has been a frontline therapy for type 2 diabetes (T2D) for many years. Its
effectiveness in T2D treatment is mostly attributed to its suppression of hepatic …
effectiveness in T2D treatment is mostly attributed to its suppression of hepatic …
Repurposing metformin for the prevention of cancer and cancer recurrence
BM Heckman-Stoddard, A DeCensi… - Diabetologia, 2017 - Springer
Multiple epidemiological studies have documented an association between metformin, used
for treatment of type 2 diabetes, and reduced cancer incidence and mortality. Cell line …
for treatment of type 2 diabetes, and reduced cancer incidence and mortality. Cell line …