Nearly all human complex traits and disease phenotypes exhibit some degree of sex
differences, including differences in prevalence, age of onset, severity or disease …

Although first identified over 70 years ago, Klinefelter syndrome (KS) continues to pose
substantial diagnostic challenges, as many patients are still misdiagnosed, or remain …

Infection caused by SARS-CoV-2 can result in severe respiratory complications and death.
Patients with a compromised immune system are expected to be more susceptible to a …

Abstract Background Knowledge about Klinefelter syndrome (KS) has increased
substantially since its first description almost 80 years ago. A variety of treatment options …

Females are more susceptible than males to many autoimmune diseases. The processes
causing this phenomenon are incompletely understood. Here, we demonstrate that aged …

The significant contributions of sex to an immune response, specifically in the context of the
sex bias observed in susceptibility to infectious and autoimmune diseases and their …

The X chromosome is known to contain the largest number of immune-related genes of the
whole human genome. For this reason, X chromosome has recently become subject of great …

The study of sexual dimorphism in psychiatric and neurodevelopmental disorders is
challenging due to the complex interplay of diverse biological, psychological, and social …

Autoimmune thyroid disease (ATD) is the most frequent cause of acquired thyroid
dysfunction, most commonly presenting either as Hashimoto's thyroiditis or Graves' Disease …

Women are more susceptible to a variety of autoimmune diseases including systemic lupus
erythematosus (SLE), multiple sclerosis (MS), primary biliary cirrhosis, rheumatoid arthritis …