Design, preparation, and characterization of effective dermal and transdermal lipid nanoparticles: a review

D Khater, H Nsairat, F Odeh, M Saleh, A Jaber… - Cosmetics, 2021 - mdpi.com
Limited permeability through the stratum corneum (SC) is a major obstacle for numerous
skin care products. One promising approach is to use lipid nanoparticles as they not only …

Advances in psoriasis physiopathology and treatments: up to date of mechanistic insights and perspectives of novel therapies based on innovative skin drug delivery …

M Sala, A Elaissari, H Fessi - Journal of Controlled Release, 2016 - Elsevier
Psoriasis is a chronic inflammatory disease affecting mainly the skin but which can be
complicated by psoriatic arthritis (PsA). This autoimmune skin disorder concerns 2–5% of …

[HTML][HTML] Pre-clinical evaluation of novel mucoadhesive bilayer patches for local delivery of clobetasol-17-propionate to the oral mucosa

HE Colley, Z Said, ME Santocildes-Romero, SR Baker… - Biomaterials, 2018 - Elsevier
Oral lichen planus (OLP) and recurrent aphthous stomatitis (RAS) are chronic inflammatory
conditions often characterised by erosive and/or painful oral lesions that have a …

Multi-component clobetasol-loaded monolithic lipid-polymer hybrid nanoparticles ameliorate imiquimod-induced psoriasis-like skin inflammation in Swiss albino mice

SS Pukale, S Sharma, M Dalela, A kumar Singh… - Acta biomaterialia, 2020 - Elsevier
Lipid-polymer hybrid nanoparticles (LPNs) exhibit several advantages over polymeric and
non-polymeric systems in terms of improved drug loading, controlled release, stability, and …

Trends in nanotechnology-based delivery systems for dermal targeting of drugs: An enticing approach to offset psoriasis

S Saleem, MK Iqubal, S Garg, J Ali… - Expert Opinion on Drug …, 2020 - Taylor & Francis
Introduction Psoriasis is identified as an inflammatory, chronic, auto-immune disease
requiring long-term treatment, imposing an unnecessary burden on the patient. A significant …

Enhanced encapsulation efficiency and controlled release of co-encapsulated Bacillus coagulans spores and vitamin B9 in gellan/κ-carrageenan/chitosan tri …

N Srivastava, AR Choudhury - International Journal of Biological …, 2023 - Elsevier
The current study, for the first time, attempts to co-encapsulate Bacillus coagulans spores as
probiotics and vitamin B9 in the polysaccharide-based matrix for their targeted delivery …

Design of finasteride-loaded nanoparticles for potential treatment of alopecia

LV Roque, IS Dias, N Cruz, A Rebelo… - Skin pharmacology and …, 2017 - karger.com
Background/Aims: Androgenetic alopecia is an extremely common dermatological disorder
affecting both men and women. Oral finasteride (FNS), a synthetic 4-aza-3-oxosteroid …

Effect of physical stimuli on hair follicle deposition of clobetasol-loaded Lipid Nanocarriers

T Angelo, N El-Sayed, M Jurisic, A Koenneke… - Scientific reports, 2020 - nature.com
Clobetasol propionate (CLO) is a potent glucocorticoid used to treat inflammation-based
skin, scalp, and hair disorders. In such conditions, hair follicles (HF) are not only the target …

Tackling the various classes of nano-therapeutics employed in topical therapy of psoriasis

SA Fereig, GM El-Zaafarany, MG Arafa… - Drug …, 2020 - Taylor & Francis
Psoriasis is a dermatological chronic skin condition with underlying autoimmune etiology. It
deeply affects patients' quality of life. Therefore, it was an interesting target for researchers …

Site-specific drug delivery in the skin for the localized treatment of skin diseases

Y Chen, X Feng, S Meng - Expert opinion on drug delivery, 2019 - Taylor & Francis
Introduction: Due to the well-organized structure and barrier function of the skin, it is
generally difficult for drugs applied directly on the surface of skin to reach their expected site …