Wall teichoic acid (WTA) and lipoteichoic acid (LTA) are structural components of Gram-
positive bacteria's peptidoglycan and cell membrane, which are mostly anionic …

Antimicrobials are useful compounds intended to eradicate or stop the growth of harmful
microorganisms. The sustained increase in the rates of antimicrobial resistance (AMR) …

Antibiotic-resistant Staphylococcus aureus remains a leading cause of antibiotic resistance-
associated mortality in the United States. Given the reality of multi-drug resistant infections, it …

Central metabolic pathways control virulence and antibiotic resistance, and constitute
potential targets for antibacterial drugs. In Staphylococcus aureus the role of the pentose …

β-lactam antibiotics interfere with cross-linking of the bacterial cell wall, but the killing
mechanism of this important class of antibiotics is not fully understood. Serendipitously we …

Bacterial cell division is a complex and highly regulated process requiring the coordination
of many different proteins. Despite substantial work in model organisms, our understanding …

Human Group IIA secreted phospholipase A2 (hGIIA) is an acute phase protein with
bactericidal activity against Gram-positive bacteria. Infection models in hGIIA transgenic …

Staphylococcus aureus is a major concern in the dairy industry due to its significance as a
pathogen causing bovine mastitis as well as a source of food poisoning. The nutrient-rich …