Clear cell renal cell carcinoma (ccRCC) is the most frequent histological kidney cancer
subtype. Over the last decade, significant progress has been made in identifying the genetic …

With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …

Cerebrovascular dysregulation is a hallmark of Alzheimer's disease (AD), but the changes
that occur in specific cell types have not been fully characterized. Here, we profile single …

The widespread expression of circular RNAs (circRNAs) is regarded as a feature of gene
expression in highly diverged eukaryotes. Recent studies have shown that circRNAs can act …

Introduction Lipidomics focuses on the in-depth analysis of lipids, which are crucial
macromolecules involved in a wide range of metabolic pathways. The increased …

Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

The steroid hormones progestagens, estrogens, androgens, and glucocorticoids as well as
their precursor cholesterol are required for successful establishment and maintenance of …

Background Inflammatory response has been recognized as a pivotal pathophysiological
process during cerebral ischemic stroke. NLRP3 inflammasome, involved in the regulation …

Urbanization drastically transforms landscapes, resulting in fragmentation, degradation, and
the loss of local biodiversity. Yet, urban environments also offer opportunities to observe …

Epidemiologic studies have, variably, shown the concomitant use of statin drugs to be
beneficial to cancer outcomes. Statin drugs have been FDA approved for three decades for …