The bacterial superantigens are protein toxins that bind to major histocompatibility complex
class II and T‐cell receptor to stimulate large numbers of T cells. The majority are produced …

Superantigens (SAgs) are the most powerful T cell mitogens ever discovered.
Concentrations of less than 0· 1 pg/ml of a bacterial superantigen are sufficient to stimulate …

CAPRI is a communitywide experiment to assess the capacity of protein‐docking methods to
predict protein–protein interactions. Nineteen groups participated in rounds 1 and 2 of …

The current status of docking procedures for predicting protein–protein interactions starting
from their three‐dimensional structure is assessed from a first major evaluation of blind …

Superantigens (SAgs) are a family of potent immunostimulatory exotoxins known to be
produced by only a few bacterial pathogens, including Staphylococcus aureus. More than …

This article describes and reviews our efforts using Hex 3.1 to predict the docking modes of
the seven target protein–protein complexes presented in the CAPRI (Critical Assessment of …

Autoimmune diseases are caused by self-reactive lymphocytes that have escaped deletion.
Here we have determined the structure of the trimolecular complex for a T cell receptor …

Abstract The ICM‐DISCO (Docking and Interface Side‐Chain Optimization) protein–protein‐
docking method is a direct stochastic global energy optimization from multiple starting …

Superantigens (SAgs) include a class of certain bacterial and viral proteins exhibiting highly
potent lymphocyte-transforming (mitogenic) activity towards human and or other mammalian …

The re-emergence of scarlet fever poses a new global public health threat. The capacity of
North-East Asian serotype M12 (emm 12) Streptococcus pyogenes (group A Streptococcus …