Diabetes mellitus, caused by the malfunction of insulin‐dependent glucose and lipid
metabolism, presents with the classical triad of symptoms: polydypsia, polyuria, and …

Gingipains are trypsin‐like cysteine proteinases produced by Porphyromonas gingivalis, a
major causative bacterium of adult periodontitis. HRgpA (95 kDa) and RgpB (50 kDa) …

Objective: The purpose of the present study was to assess the relation between clinical
parameters and concentrations of the key (IL‐1β, TNF‐α, IL‐2, IFN‐γ, IL‐4, IL‐10) cytokines …

Background: Various cytokines have been identified at sites of chronic inflammation such as
periodontitis. Cytokines are synthesized in response to bacteria and their products, inducing …

Background The objective of this systematic review was to systematically investigate
whether there is an association between inflammatory bowel disease (IBD) and oral health …

Discusses the role of bacterial proteinases in matrix destruction and modulation of host
responses. Evasion of host defense mechanisms; Mechanism of gingipain inference with …

The presence of periodontal diseases (PDs) often strongly correlates with other severe
chronic inflammatory conditions, including cardiovascular disease, diabetes, and arthritis …

Objectives: To analyze the anti‐inflammatory effects of Lactobacillus brevis extracts on
periodontitis patients and to investigate the involved mechanisms in vitro on activated …

Background: Current publications present contradictory findings regarding interleukin-8 (IL-
8) levels in patients with chronic periodontitis (CP). This systematic review compile …

Porphyromonas gingivalis, a gram-negative anaerobe, is a leading etiological agent in
periodontitis. This infectious pathogen can induce a dysbiotic, proinflammatory state within …