Binge eating, overeating and food addiction: Approaches for examining food overconsumption in laboratory rodents

RM Brown, MH James - Progress in Neuro-Psychopharmacology and …, 2023 - Elsevier
Overeating ranges in severity from casual overindulgence to an overwhelming drive to
consume certain foods. At its most extreme, overeating can manifest as clinical diagnoses …

Bored at home?—A systematic review on the effect of environmental enrichment on the welfare of laboratory rats and mice

P Mieske, U Hobbiesiefken… - Frontiers in Veterinary …, 2022 - frontiersin.org
Boredom is an emotional state that occurs when an individual has nothing to do, is not
interested in the surrounding, and feels dreary and in a monotony. While this condition is …

Locally induced adipose tissue browning by microneedle patch for obesity treatment

Y Zhang, Q Liu, J Yu, S Yu, J Wang, L Qiang, Z Gu - ACS nano, 2017 - ACS Publications
Obesity is one of the most serious public health problems in the 21st century that may lead to
many comorbidities such as type-2 diabetes, cardiovascular diseases, and cancer. Current …

Intestinal microbiome of broiler chickens after use of nanoparticles and metal salts

Е Yausheva, S Miroshnikov, Е Sizova - Environmental science and …, 2018 - Springer
The research included the study of influence of ultrafine particle preparations (nanoparticles
of copper, zinc, iron, CuZn alloy) and metal salts (iron pyrophosphate, copper asparginate …

Repeated dose (28-day) administration of silver nanoparticles of varied size and coating does not significantly alter the indigenous murine gut microbiome

LA Wilding, CM Bassis, K Walacavage… - …, 2016 - Taylor & Francis
Silver nanoparticles (AgNPs) have been used as antimicrobials in a number of applications,
including topical wound dressings and coatings for consumer products and biomedical …

The effects of group and single housing and automated animal monitoring on urinary corticosterone levels in male C57 BL/6 mice

R Kamakura, M Kovalainen, J Leppäluoto… - Physiological …, 2016 - Wiley Online Library
Mice are used extensively in physiological research. Automated home‐cage systems have
been developed to study single‐housed animals. Increased stress by different housing …

A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis

Q Chen, L Huang, D Pan, K Hu, R Li… - Nature …, 2022 - nature.com
The signaling mechanisms underlying adipose thermogenesis have not been fully
elucidated. Particularly, the involvement of adipokines that are selectively expressed in …

Payload-binding Fab fragments increase the therapeutic index of MMAE antibody–drug conjugates

BM Bordeau, TD Nguyen, JR Polli, P Chen… - Molecular cancer …, 2023 - AACR
Monomethyl auristatin E (MMAE) is a potent tubulin inhibitor that is used as the payload for
four FDA-approved antibody–drug conjugates (ADC). Deconjugated MMAE readily diffuses …

Methods for the Comprehensive in vivo Analysis of Energy Flux, Fluid Homeostasis, Blood Pressure, and Ventilatory Function in Rodents

JJ Reho, P Nakagawa, GC Mouradian Jr… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular disease represents the leading cause of death in the United States, and
metabolic diseases such as obesity represent the primary impediment to improving …

Evaluation of the neutrophil-lymphocyte ratio as a measure of distress in rats

MP Swan, DL Hickman - Lab animal, 2014 - nature.com
The ability to evaluate distress in laboratory animals is needed in order to ensure that
husbandry and experimental procedures do not negatively impact animal welfare. Accurate …