Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and
has a high fatality rate. Genetic and epigenetic aberrations are commonly observed in HCC …

Liver cancer is a global health challenge, causing a significant social-economic burden.
Hepatocellular carcinoma (HCC) is the predominant type of primary liver cancer, which is …

Liver fibrosis is an intrinsic repair process of chronic injury with excessive deposition of
extracellular matrix. As an early stage of various liver diseases, liver fibrosis is a reversible …

Background Studies demonstrate the impact of diet and physical activity on epigenetic
biomarkers, specifically DNA methylation. However, no intervention studies have examined …

Hepatocellular carcinoma (HCC) is characterized by high prevalence, morbidity, and
mortality. Liver cancer is the sixth most common cancer worldwide; and its subtype, HCC …

Br east Ca ncer 1 (BRCA1) gene is a well-characterized tumor suppressor gene, mutations
of which are primarily found in women with breast and ovarian cancers. B RCA1-a ssociated …

Hepatocellular carcinoma (HCC) is mostly triggered by environmental and life-style factors
and may involve epigenetic aberrations. However, a comprehensive documentation of the …

Pollutants, such as toxic metals, negatively influence organismal health and performance,
even leading to population collapses. Studies in model organisms have shown that …

Object: Maternal embryonic leucine zipper kinase (MELK) is involved in the development
and progression of various cancers. This work investigated the usefulness of MELK in the …

Hepatitis B virus (HBV) specifically infects liver cells, leading to progressive liver cirrhosis
and significantly increasing the risk of hepatocellular carcinoma (HCC). The maturity of …