Agnostic sequencing for detection of viral pathogens

NPG Gauthier, SD Chorlton, M Krajden… - Clinical microbiology …, 2023 - Am Soc Microbiol
The advent of next-generation sequencing (NGS) technologies has expanded our ability to
detect and analyze microbial genomes and has yielded novel molecular approaches for …

Assessment and validation of enrichment and target capture approaches to improve Mycobacterium tuberculosis WGS from direct patient samples

BC Mann, KR Jacobson, Y Ghebrekristos… - Journal of Clinical …, 2023 - Am Soc Microbiol
ABSTRACT Within-host Mycobacterium tuberculosis (Mtb) diversity may detect antibiotic
resistance or predict tuberculosis treatment failure and is best captured through sequencing …

Direct genome sequencing of respiratory viruses from low viral load clinical specimens using the target capture sequencing technology

N Takemae, Y Kuba, K Oba… - Microbiology Spectrum, 2024 - journals.asm.org
The use of metagenomic next-generation sequencing technology to obtain complete viral
genome sequences directly from clinical samples with low viral load remains challenging …

Comparison of the performance of two targeted metagenomic virus capture probe-based methods using reference control materials and clinical samples

K Mourik, I Sidorov, EC Carbo… - Journal of Clinical …, 2024 - Am Soc Microbiol
Viral enrichment by probe hybridization has been reported to significantly increase the
sensitivity of viral metagenomics. This study compares the analytical performance of two …

Molecular detection of respiratory viruses: an observational study on respiratory co-infections in children and adults

TJPG Bandeira, ALS Oliveira, LFP Martins… - Brazilian Journal of …, 2024 - Springer
Respiratory tract infection (RTI) is the most important cause of visiting both public and private
medical care services. During the decade preceding Covid-19, in developing countries …

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K Mourik, I Sidoro, EC Carbo… - … Vries,.. C. de, 2024 - scholarlypublications …
Viral enrichment by probe hybridization has been reported to significantly increase the
sensitivity of viral metagenomics. This study compares the analytical performance of two …