Mechanistic evaluation of phytochemicals in breast cancer remedy: current understanding and future perspectives

M Younas, C Hano, N Giglioli-Guivarc'h, BH Abbasi - RSC advances, 2018 - pubs.rsc.org
Breast cancer is one of the most commonly diagnosed cancers around the globe and
accounts for a large proportion of fatalities in women. Despite the advancement in …

Therapeutic potential of quercetin on human breast cancer in different dimensions

N Kasiri, M Rahmati, L Ahmadi, N Eskandari… - …, 2020 - Springer
Background There has been an extensive range of incidence and mortality of breast cancer
(BC), and the comprehensively available treatments for BC have not been completely …

[HTML][HTML] Natural products and derivatives for breast cancer treatment: From drug discovery to molecular mechanism

J Zhang, Y Wu, Y Li, S Li, J Liu, X Yang, G Xia, G Wang - Phytomedicine, 2024 - Elsevier
Background Breast cancer stands as the most common malignancy among women globally
and a leading cause of cancer-related mortality. Conventional treatments, such as surgery …

Chemoprevention of prostate cancer cells by vitamin C plus quercetin: role of Nrf2 in inducing oxidative stress

A Abbasi, Z Mostafavi-Pour, A Amiri… - Nutrition and …, 2021 - Taylor & Francis
To assess the effect of sequential treatment with Vitamin C (VC) and Quercetin (Q) on Nrf2-
related oxidative stress in PC3 and DU145 cells, viability was measured by MTT assay …

Cocrystal formation of betulinic acid and ascorbic acid: Synthesis, physico-chemical assessment, antioxidant, and antiproliferative activity

M Nicolov, RM Ghiulai, M Voicu, M Mioc… - Frontiers in …, 2019 - frontiersin.org
Betulinic acid (BA) was demonstrated to be a very promising anticancer agent against
various tumor cell lines such as breast, colon, lung, and brain. Despite its strong cytotoxic …

Forskolin improves sensitivity to doxorubicin of triple negative breast cancer cells via Protein Kinase A-mediated ERK1/2 inhibition

M Illiano, L Sapio, A Salzillo, L Capasso, I Caiafa… - Biochemical …, 2018 - Elsevier
Triple negative breast cancer (TNBC) is an invasive, metastatic, highly aggressive tumor.
Cytotoxic chemotherapy represents the current treatment for TNBC. However, relapse and …

In-vitro analysis of glucose and quercetin effects on m-TOR and Nrf-2 expression in HepG2 cell line (diabetes and cancer connection)

A Yarahmadi, F Khademi, Z Mostafavi-Pour… - Nutrition and …, 2018 - Taylor & Francis
Some types of cancers show a strong relationship with diabetes and play a central role in
mortality in the patient population suffering from diabetes mellitus. In this study, HepG2 cells …

Prognostic value and biological role of mir-126 in breast cancer

SR Soofiyani, K Hosseini, T Ebrahimi… - …, 2022 - ingentaconnect.com
In eukaryotic organisms such as humans, some noncoding single-stranded RNAs (ncRNAs)
contribute to regulating the expression of some genes before and after the transcription …

Telmisartan anti‐cancer activities mechanism through targeting N‐cadherin by mimicking ADH‐1 function

M Khorsand, S Khajeh, M Eslami… - Journal of Cellular …, 2022 - Wiley Online Library
This study aimed to investigate if Telmisartan as a novel N‐cadherin antagonist, can
overcome cell migration of cancer cells. We investigated the mechanism and influence of …

[HTML][HTML] Identification of natural products and FDA-approved drugs for targeting cancer stem cell (CSC) propagation

G Bonuccelli, F Sotgia, MP Lisanti - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
Here, we report the identification of key compounds that effectively inhibit the anchorage-
independent growth and propagation of cancer stem cells (CSCs), as determined via …